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Mouse Ephrin B, pan Monoclonal Antibody

Ephrin B, pan

Reactivity
Chicken, Human
Applications
ELISA, Western Blot, Immunoprecipitation
Purity
Affinity Purified
Purified by Protein A chromatography
Synonyms
Ephrin B; pan; Monoclonal Antibody; Anti -Ephrin B; anti-Ephrin B; pan antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Chicken, Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
6A72
Specificity
Recognizes over-expressed and endogenous ephrin-B, as well as phosphorylated ephrin-B. On Western Blots it identifies a band at ~50-60kD. Species crossreactivity
Purity/Purification
Affinity Purified
Purified by Protein A chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-Ephrin B, pan antibody
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
Application Notes
Suitable for use in Western Blot, Immunoprecipitation and ELISA.
Recommended Dilutions: Optimal dilutions to be determined by the researcher.
Immunogen
Synthetic peptide corresponding to the ephrin-B sequence.
Positive Control
Human 293T and MCF10A lysates, chicken cell lysates
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Ephrin B, pan antibody
Ephrins are a family of proteins that bind to the tyrosine kinase Eph receptor. Their function is still under investigation, but they are suspected to play an important role in morphogenesis. The ephrins can be grouped into two classes: those that are tethered to the membrane by a GPI linkage, called ephrin-A proteins (which bind to EphA receptors), and those with a membrane-spanning region, called ephrin-B proteins (which bind to EphB receptors). Ephrins are expressed in the embryo in various tissues in the forming mesoderm, endoderm and nervous system in all of the vertebrate species in which they have been identified. Ephrin-B3, also known as NLERK-2, Elk-L3, EFL-6, ELF-3 and LERK-8 is a member of the ephrin-B protein family. Ephrin-B3 binds EphA4, EphB1, EphB2 and EphB33,. Ephrin-B1 is one of the transmembrane ligands for the EphB2 receptor. In the embryo, EphB2 and ephrin-B1 participate in neuronal axon guidance, neural crest cell migration, the formation of blood vessels and the development of facial structures and the inner ear. EphB2 and ephrin-B1 can both signal through their cytoplasmic domains and become phosphorylated when bound to each other. Tyrosine phosphorylation regulates EphB2 signaling and likely also ephrin-B1 signaling.
Product Categories/Family for anti-Ephrin B, pan antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
epoxide hydrolase EphB

Similar Products

Product Notes

The Ephrin B, pan (Catalog #AAA602769) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Ephrin B, pan reacts with Chicken, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ephrin B, pan can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP). Suitable for use in Western Blot, Immunoprecipitation and ELISA. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Ephrin B, pan for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ephrin B, pan, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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