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Rat EB3 Monoclonal Antibody | anti-EB3 antibody

Anti-EB3 Antibody

Applications
ELISA
Purity
Affinity purified
Synonyms
EB3; Monoclonal Antibody; Anti-EB3 Antibody; Anti-human EB3 Antibody; anti-EB3 antibody
Ordering
For Research Use Only!
Host
Rat
Clonality
Monoclonal
Isotype
IgG2a
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
1ug/ul (varies by lot)
Sequence Length
281
Applicable Applications for anti-EB3 antibody
Immunofluorescent Staining, ELISA (EIA)
Application Notes
ELISA: 1:1000
Immunofluorescent staining 1:200
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Immunogen
Full-length human EB3 fused to GST
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
References
Komarova Y, Lansbergen G, Galjart N, Grosveld F, Borisy GG and Akhmanova A. 2005. EB1 and EB3 Control CLIP Dissociation from the Ends of Growing Microtubules. Mol. Biol. Cell. 16:5334-45.

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
30,380 Da
NCBI Official Full Name
EB3 protein
UniProt Protein Name
Microtubule-associated protein RP/EB family member 3
UniProt Gene Name
MAPRE3
UniProt Entry Name
MARE3_HUMAN

Uniprot Description

EB3: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. Belongs to the MAPRE family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding

Chromosomal Location of Human Ortholog: 2p23.3-p23.1

Cellular Component: microtubule cytoskeleton; cytoplasmic microtubule; perinuclear region of cytoplasm; cytoplasm; midbody

Molecular Function: protein binding; microtubule binding

Biological Process: mitosis; positive regulation of cyclin-dependent protein kinase activity; cell division; positive regulation of transcription, DNA-dependent

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Product Notes

The EB3 mapre3 (Catalog #AAA417006) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's EB3 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescent Staining, ELISA (EIA). ELISA: 1:1000 Immunofluorescent staining 1:200. Researchers should empirically determine the suitability of the EB3 mapre3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EB3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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