Mouse DRAK1 Monoclonal Antibody | anti-STK17A antibody

DRAK1 (DAP Kinase-related Apoptosis-inducing Protein Kinase 1)

Cat. Num. AAA601136

• Gene Names: STK17A; DRAK1; STK17A
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: DRAK1; Monoclonal Antibody; DRAK1 (DAP Kinase-related Apoptosis-inducing Protein Kinase 1); Anti -DRAK1 (DAP Kinase-related Apoptosis-inducing Protein Kinase 1); anti-STK17A antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 8C120
• Specificity: Recognizes human DRAK1.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

• Applicable Applications for anti-STK17A antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western Blotting: 1:1000-1:2000
• Immunogen: Partial sequence of recombinant full-length protein to human DRAK1
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Western Blot analysis using MBS601136)

Product Categories/Family for anti-STK17A antibody

Antibodies; Abs to Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 3834354
• NCBI GeneID: 9263
• UniProt Accession #: Q9UEE5; Q8IVC8; A4D1V6; Q75MK4; Q86UI9; Q9NZ11
• Molecular Weight: 46,558 Da
• NCBI Official Full Name: DRAK1
• NCBI Official Synonym Full Names: serine/threonine kinase 17a
• NCBI Official Symbol: STK17A
• NCBI Official Synonym Symbols: DRAK1; STK17A
• NCBI Protein Information: serine/threonine-protein kinase 17A; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing); DAP kinase-related apoptosis-inducing protein kinase 1
• UniProt Protein Name: Serine/threonine-protein kinase 17A
• Protein Family: Serine/threonine-protein kinase
• UniProt Gene Name: STK17A
• UniProt Synonym Gene Names: DRAK1
• UniProt Entry Name: ST17A_HUMAN

NCBI Description

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq]

Uniprot Description

DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, CAMK; Kinase, protein; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleus

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation