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Western Blot (WB) (Western Blot analysis of MBS613094 in MOLT4 (A), A431 (B), and 3T3 (C) whole cell lysates with anti-DRAK1 at 1:500 dilution.)

Rabbit DRAK1 Polyclonal Antibody | anti-STK17A antibody

DRAK1, NT (DAP Kinase-related Apoptosis-inducing Protein Kinase 1)

Gene Names
STK17A; DRAK1; STK17A
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity Purified
Immunoaffinity purified IgG
Synonyms
DRAK1; Polyclonal Antibody; NT (DAP Kinase-related Apoptosis-inducing Protein Kinase 1); Anti -DRAK1; anti-STK17A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human, mouse and rat DRAK1 (NT)
Purity/Purification
Affinity Purified
Immunoaffinity purified IgG
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-STK17A antibody
Western Blot (WB)
Immunogen
Peptide corresponding to amino acids 5 to 19 of human DRAK1 (1).
Preparation and Storage
-20 degree C

Western Blot (WB)

(Western Blot analysis of MBS613094 in MOLT4 (A), A431 (B), and 3T3 (C) whole cell lysates with anti-DRAK1 at 1:500 dilution.)

Western Blot (WB) (Western Blot analysis of MBS613094 in MOLT4 (A), A431 (B), and 3T3 (C) whole cell lysates with anti-DRAK1 at 1:500 dilution.)

Immunohistochemistry (IHC)

(Immunohistochemical staining of Molt4 cells using MBS613094 at 2ug/ml.)

Immunohistochemistry (IHC) (Immunohistochemical staining of Molt4 cells using MBS613094 at 2ug/ml.)
Related Product Information for anti-STK17A antibody
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).
Product Categories/Family for anti-STK17A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
46,558 Da
NCBI Official Full Name
DRAK1
NCBI Official Synonym Full Names
serine/threonine kinase 17a
NCBI Official Symbol
STK17A
NCBI Official Synonym Symbols
DRAK1; STK17A
NCBI Protein Information
serine/threonine-protein kinase 17A; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing); DAP kinase-related apoptosis-inducing protein kinase 1
UniProt Protein Name
Serine/threonine-protein kinase 17A
UniProt Gene Name
STK17A
UniProt Synonym Gene Names
DRAK1
UniProt Entry Name
ST17A_HUMAN

NCBI Description

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq]

Uniprot Description

DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleus

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation

Research Articles on STK17A

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Product Notes

The STK17A stk17a (Catalog #AAA613094) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DRAK1, NT (DAP Kinase-related Apoptosis-inducing Protein Kinase 1) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DRAK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the STK17A stk17a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRAK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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