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Mouse DMC1 Monoclonal Antibody | anti-DMC1 antibody

DMC1 (Disrupted Meiotic cDNA 1 Homolog, dJ199H16.1, DMC 1, DMC1H, HsLim15, Meiotic Recombination Protein DMC1/LIM15 Homolog)

Gene Names
DMC1; DMC1H; LIM15; HsLim15; MGC150472; MGC150473; dJ199H16.1
Reactivity
Bovine, Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunofluorescence
Purity
Mouse ascites
Synonyms
DMC1; Monoclonal Antibody; DMC1 (Disrupted Meiotic cDNA 1 Homolog; dJ199H16.1; DMC 1; DMC1H; HsLim15; Meiotic Recombination Protein DMC1/LIM15 Homolog); Anti -DMC1 (Disrupted Meiotic cDNA 1 Homolog; anti-DMC1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Bovine, Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
8J1306
Specificity
Specific for DMC1 - does not crossreact with the related protein Rad51. Species Crossreactivity: Crossreacts with Human, Mouse, Rat and bovine. Not yet tested in other species.
Purity/Purification
Mouse ascites
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Applicable Applications for anti-DMC1 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation.
Immunogen
Recombinant fusion protein (Human).
Cellular Localization
Nuclear
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-DMC1 antibody
Rad51 and disrupted meiotic cDNA1 (Dmc1) are the two eukaryotic DNA recombinases that participate in homology search and strand exchange reactions during homologous recombination mediated DNA repair.
Product Categories/Family for anti-DMC1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
37,681 Da
NCBI Official Full Name
DMC1
NCBI Official Synonym Full Names
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
NCBI Official Symbol
DMC1
NCBI Official Synonym Symbols
DMC1H; LIM15; HsLim15; MGC150472; MGC150473; dJ199H16.1
NCBI Protein Information
meiotic recombination protein DMC1/LIM15 homolog; DMC1 homologue; OTTHUMP00000199098; OTTHUMP00000199222; disrupted meiotic cDNA1, yeast, homolog of
UniProt Protein Name
Meiotic recombination protein DMC1/LIM15 homolog
UniProt Gene Name
DMC1
UniProt Synonym Gene Names
DMC1H; LIM15
UniProt Entry Name
DMC1_HUMAN

NCBI Description

The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined. [provided by RefSeq]

Uniprot Description

DMC1: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Belongs to the RecA family. DMC1 subfamily.

Protein type: DNA repair, damage; Cell cycle regulation; Cell development/differentiation

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: chromosome, telomeric region; condensed nuclear chromosome; chromosome; nucleus

Molecular Function: DNA-dependent ATPase activity; protein binding; DNA binding; ATP binding

Biological Process: meiosis; male meiosis I; ovarian follicle development; meiotic recombination; synapsis; female gamete generation; spermatogenesis; oocyte maturation; spermatid development

Research Articles on DMC1

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Product Notes

The DMC1 dmc1 (Catalog #AAA603391) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DMC1 (Disrupted Meiotic cDNA 1 Homolog, dJ199H16.1, DMC 1, DMC1H, HsLim15, Meiotic Recombination Protein DMC1/LIM15 Homolog) reacts with Bovine, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DMC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF). Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Researchers should empirically determine the suitability of the DMC1 dmc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DMC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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