Testing Data #1
(Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:FITC (MBS224383) )
Rat CLEC2 Monoclonal Antibody | anti-CLEC2 antibody
RAT ANTI MOUSE CLEC2:RPE
Gene Names
Clec1b; Clec2; Clec-2; 1810061I13Rik
Applications
Flow Cytometry, Functional Assay
Synonyms
CLEC2; Monoclonal Antibody; RAT ANTI MOUSE CLEC2:RPE; anti-CLEC2 antibody
Host
Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
17D9
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Sequence Length
197
Applicable Applications for anti-CLEC2 antibody
Flow cytometry (FC/FACS)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat
Flow Cytometry: Minimum Dilution: Neat
Reconstitution
Reconstitute with 1ml distilled water
Perservative Stabilisers
Perservative Stabilisers
Immunogen
RBL-2H3 cells stably expressing HA-tagged mouse CLEC2.
Fusion Partners
Fusion Partners
Target Species
Mouse
Preparation and Storage
Prior to reconstitution store at 4 degree C. After reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Shelf Life: 12 months from date of reconstitution.
Testing Data #1
(Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:FITC (MBS224383) )
Testing Data #1
(Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:FITC (MBS224383) )
Testing Data #2
(Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:RPE (MBS224416) )
Testing Data #2
(Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:RPE (MBS224416) )
Related Product Information for anti-CLEC2 antibody
Rat anti Mouse CLEC2 antibody, clone 17D9 recognizes mouse C-type lectin domain family 1 member B, also known as CLEC2 or CLEC1B. CLEC2 acts as a receptor for rhodocytin, a platelet-aggregating protein found in snake venom. CLEC2 expression is not restricted to platelets and also acts as an activation receptor on neutrophils.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,870 Da
NCBI Official Full Name
C-type lectin domain family 1 member B isoform 2
NCBI Official Synonym Full Names
C-type lectin domain family 1, member b
NCBI Official Symbol
Clec1b
NCBI Official Synonym Symbols
Clec2; Clec-2; 1810061I13Rik
NCBI Protein Information
C-type lectin domain family 1 member B; C-type lectin-like receptor 2
UniProt Protein Name
C-type lectin domain family 1 member B
UniProt Gene Name
Clec1b
UniProt Synonym Gene Names
Clec2; CLEC-2
UniProt Entry Name
CLC1B_MOUSE
Uniprot Description
CLEC1B: Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: membrane; integral to plasma membrane; integral to membrane
Molecular Function: transmembrane receptor activity; carbohydrate binding
Biological Process: cell surface receptor linked signal transduction; platelet formation; signal transduction
Research Articles on CLEC2
Similar Products
Product Notes
The CLEC2 clec1b (Catalog #AAA224416) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CLEC2 can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS). Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat. Researchers should empirically determine the suitability of the CLEC2 clec1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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