ELISA (EIA)
Mouse anti-Human CEA Monoclonal Antibody | anti-CEACAM5 antibody
Anti-CEA Antibody (3C5C10)
Gene Names
CEACAM5; CEA; CD66e
Reactivity
Human
Applications
ELISA
Purity
Protein A purification
Synonyms
CEA; Monoclonal Antibody; Anti-CEA Antibody (3C5C10); Meconium antigen 100; CD_antigen: CD66e; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; anti-CEACAM5 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1, kappa
Clone Number
3C5C10
Specificity
Monoclonal antibody to detect CEA. CEA monoclonal antibodies (Clone# 1A5C3 and 3C5C10) recognize human native CEA protein.
Purity/Purification
Protein A purification
Form/Format
Colorless liquid. In PBS buffer, pH7.4, containing 0.02% sodium azide
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-CEACAM5 antibody
ELISA (EIA)
Application Notes
ELISA Capture: 1-10ug/ml
ELISA Detection: 0.05-0.2ug/ml
ELISA Detection: 0.05-0.2ug/ml
Sensitivity
The limit of detection for antibody pairs is 0.5 ng/ml
Immunogen
Native CEA protein
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use
Shelf life: ~12 months
The antibody solution should be gently mixed before use
Shelf life: ~12 months
ELISA (EIA)
ELISA (EIA)
Related Product Information for anti-CEACAM5 antibody
Carcinoembryonic antigen (CEA) is a complex glycoprotein of molecular weight 200 kDa. In healthy adults, less than 5 ng/ml of CEA is found in the serum. Elevation of CEA antigen is found in the blood of patients with cancer of the lung, liver, pancreas, breast, cervix, prostate and so on. CEA measurement is mainly used as a tumor marker to identify recurrences after surgical resection, or localize cancer spread though dosage of biological fluids. The CEA blood test is not reliable for detecting cancer. CEA levels may also be raised in some conditions like ulcerative colitis, pancreatitis and cirrhosis.CEA Antibody is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with native human CEA protein
Product Categories/Family for anti-CEACAM5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
76,795 Da
NCBI Official Full Name
Carcinoembryonic antigen-related cell adhesion molecule 5
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 5
NCBI Official Symbol
CEACAM5
NCBI Official Synonym Symbols
CEA; CD66e
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 5
Protein Family
UniProt Gene Name
CEACAM5
UniProt Synonym Gene Names
CEA; CEA
UniProt Entry Name
CEAM5_HUMAN
NCBI Description
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009]
Uniprot Description
CEACAM5: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family.
Protein type: Membrane protein, integral; Immunoglobulin superfamily; Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 19q13.1-q13.2
Cellular Component: basolateral plasma membrane; integral to plasma membrane
Molecular Function: identical protein binding; protein homodimerization activity
Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis
Research Articles on CEACAM5
Similar Products
Product Notes
The CEACAM5 ceacam5 (Catalog #AAA847230) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-CEA Antibody (3C5C10) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CEA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA Capture: 1-10ug/ml ELISA Detection: 0.05-0.2ug/ml. Researchers should empirically determine the suitability of the CEACAM5 ceacam5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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