Rat anti-Canine CD8 Monoclonal Antibody | anti-CD8 antibody

CD8 (AP)

Cat. Num. AAA6247752

• Reactivity: Canine
• Applications: Immunohistochemistry
• Purity: Purified by protein G affinity chromatography from tissue culture supernatant.
• Synonyms: CD8; Monoclonal Antibody; CD8 (AP); anti-CD8 antibody

• Host: Rat
• Reactivity: Canine
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: YCATE55.9
• Specificity: Recognizes canine CD8.
• Purity/Purification: Purified by protein G affinity chromatography from tissue culture supernatant.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.

• Applicable Applications for anti-CD8 antibody: Immunohistochemistry (IHC)
• Immunogen: Canine CD8 alpha chimeric human IgG1 Fc fusion protein.
• Conjugate: AP
• Preparation and Storage: Store at 4 degree C. Do Not Freeze.

Testing Data

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Testing Data

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Testing Data

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Product Categories/Family for anti-CD8 antibody

Antibodies; CD Markers

References

1. Cobbold, S and Metcalfe, S. (1994) Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 43: 137-154. 2. Gorman, S. et al. (1994) Isolation and expression of cDNA encoding the canine CD4 and CD8a antigens. Tissue Antigens. 43:184-188. 3. Watson, C. J. E. et al. (1993) CD4 and CD8 monoclonal antibody therapy: strategies to prolong renal allograft survival in the dog. Brit. J. Surg. 80: 1389-1392. 4. Papadogiannakis, E.I. et al. (2009) Determination of intracellular cytokines IFN-gamma and IL-4 in canine T lymphocytes by flow cytometry following whole-blood culture.Can J Vet Res. 73: 137-143. 5. Benyacoub, J. et al. (2003) Supplementation of food with Enterococcus faecium (SF68) stimulates immune functions in young dogs.J Nutr. 133: 1158-62. 6. Bird, R.C. et al. (2010) An autologous dendritic cell canine mammary tumor hybrid-cell fusion vaccine.Cancer Immunol Immunother. 60: 87-97. 7. Bund, D. et al. (2010) Canine-DCs using different serum-free methods as an approach to provide an animal-model for immunotherapeutic strategies.Cell Immunol. 263: 88-98. 8. Estrela-Lima, A. et al. (2010) Immunophenotypic features of tumor infiltrating lymphocytes from mammary carcinomas in female dogs associated with prognostic factors and survival rates.BMC Cancer. 10: 256. 9. Huang, Y.C. et al. (2008) CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells.J Leukoc Biol. 84: 1501-10. 10. Kornegay, J.N. et al. (2010) Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs.Mol Ther. 18: 1501-8. 11. Pichavant, C. et al. (2010) Expression of dog microdystrophin in mouse and dog muscles by gene therapy.Mol Ther. 18: 1002-9. 12. Pinheiro, D. et al (2011) Phenotypic and functional characterization of a CD4(+) CD25(high) FOXP3(high) regulatory T-cell population in the dog.Immunology. 132: 111-22. 12. Reis, A.B. et al. (2006) Phenotypic features of circulating leucocytes as immunological markers for clinical status and bone marrow parasite density in dogs naturally infected by Leishmania chagasi.Clin Exp Immunol. 146: 303-11.

NCBI and Uniprot Product Information

• NCBI GI #: 55742790
• NCBI GeneID: 403157
• NCBI Accession #: NP_001002935.1
• NCBI GenBank Nucleotide #: NM_001002935.2
• UniProt Accession #: P33706
• Molecular Weight: 26,036 Da
• NCBI Official Full Name: T-cell surface glycoprotein CD8 alpha chain
• NCBI Official Symbol: CD8A
• NCBI Protein Information: T-cell surface glycoprotein CD8 alpha chain; CD8 antigen, alpha polypeptide (p32)
• UniProt Protein Name: T-cell surface glycoprotein CD8 alpha chain
• Protein Family: CD81 antigen
• UniProt Gene Name: CD8A
• UniProt Entry Name: CD8A_CANFA