Rabbit anti-Human FUCA2 Polyclonal Antibody | anti-FUCA2 antibody

FUCA2 (Fucosidase alpha-L-2 Plasma, Alpha-L-fucoside Fucohydrolase 2, Alpha-L-fucosidase 2, dJ20N2.5, MGC1314, Plasma alpha-L-fucosidase, PSEC0151, RP1-20N2.5, UNQ227/PRO260) APC

Cat. Num. AAA6378989

• Gene Names: FUCA2; dJ20N2.5
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: FUCA2; Polyclonal Antibody; FUCA2 (Fucosidase alpha-L-2 Plasma; Alpha-L-fucoside Fucohydrolase 2; Alpha-L-fucosidase 2; dJ20N2.5; MGC1314; Plasma alpha-L-fucosidase; PSEC0151; RP1-20N2.5; UNQ227/PRO260) APC; anti-FUCA2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FUCA2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 1696

• Applicable Applications for anti-FUCA2 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human FUCA2, aa1-467 (AAH03060.1).
• Immunogen Sequence: MRPQELPRLAFPLLLLLLLLLPPPPCPAHSATRFDPTWESLDARQLPAWFDQAKFGIFIHWGVFSVPSFGSEWFWWYWQKEKIPKYVEFMKDNYPPSFKYEDFGPLFTAKFFNANQWADIFQASGAKYIVLTSKHHEGFTLWGSEYSWNWNAIDEGPKRDIVKELEVAIRNRTDLRFGLYYSLFEWFHPLFLEDESSSFHKRQFPVSKTLPELYELVNNYQPEVLWSDGDGGAPDQYWNSTGFLAWLYNESPVRGTVVTNDRWGAGSICKHGGFYTCSDRYNPGHLLPHKWENCMTIDKLSWGYRREAGISDYLTIEELVKQLVETVSCGGNLLMNIGPTLDGTISVVFEERLRQVGSWLKVNGEAIYETYTWRSQNDTVTPDVWYTSKPKEKLVYAIFLKWPTSGQLFLGHPKAILGATEVKLLGHGQPLNWISLEQNGIMVELPQLTIHQMPCKWGWALALTNVI
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of FUCA2 expression in transfected 293T cell line by FUCA2 polyclonal antibody. Lane 1: FUCA2 transfected lysate (54.1kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-FUCA2 antibody

Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.

Product Categories/Family for anti-FUCA2 antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 34782784
• NCBI GeneID: 2519
• NCBI Official Full Name: Homo sapiens fucosidase, alpha-L- 2, plasma, mRNA
• NCBI Official Synonym Full Names: alpha-L-fucosidase 2
• NCBI Official Symbol: FUCA2
• NCBI Official Synonym Symbols: dJ20N2.5
• NCBI Protein Information: plasma alpha-L-fucosidase
• Protein Family: Plasma alpha-L-fucosidase

NCBI Description

This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010]