Rabbit CD79A Monoclonal Antibody | anti-CD79A antibody

Recombinant Anti-CD79A Antibody, Rabbit Monoclonal

Cat. Num. AAA8100104

• Gene Names: CD79A; IGA; MB-1
• Reactivity: Human, Cynomolgus
• Applications: Immunohistochemistry
• Purity: Protein A
• Synonyms: CD79A; Monoclonal Antibody; Recombinant Anti-CD79A Antibody; Rabbit Monoclonal; CD79A/Ig-alpha Antibody; Rabbit MAb; CD79a molecule; immunoglobulin-associated alpha; Anti-IGA Antibody; Anti-MB-1 Antibody; anti-CD79A antibody

• Host: Rabbit
• Reactivity: Human, Cynomolgus
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: 001
• Specificity: Human CD79A
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-CD79A antibody: Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: IHC-P: 1:1000-1:20,000
• Antibody Type: Recombinant Antibody
• Immunogen: A synthetic peptide corresponding to the C-terminus of the human CD79a
• Conjugation: Unconjugated
• Preparation: This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the C-terminus of the human CD79a.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining CD79a in human spleen with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections).)

Immunohistochemistry (IHC)

(Immunochemical staining CD79a in human appendix with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections).)

Immunohistochemistry (IHC)

(Immunochemical staining CD79a in cynomolgus spleen with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)

Immunohistochemistry (IHC)

(Immunochemical staining CD79a in cynomolgus lymph node with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)

NCBI and Uniprot Product Information

• NCBI GI #: 4502685
• NCBI GeneID: 973
• NCBI Accession #: NP_001774.1
• NCBI GenBank Nucleotide #: NM_001783.3
• UniProt Accession #: P11912; Q53FB8; A0N775
• Molecular Weight: 25,038 Da
• NCBI Official Full Name: B-cell antigen receptor complex-associated protein alpha chain isoform 1
• NCBI Official Synonym Full Names: CD79a molecule, immunoglobulin-associated alpha
• NCBI Official Symbol: CD79A
• NCBI Official Synonym Symbols: IGA; MB-1
• NCBI Protein Information: B-cell antigen receptor complex-associated protein alpha chain; ig-alpha; MB-1 membrane glycoprotein; surface IgM-associated protein; CD79a antigen (immunoglobulin-associated alpha); membrane-bound immunoglobulin-associated protein
• UniProt Protein Name: B-cell antigen receptor complex-associated protein alpha chain
• Protein Family: B-cell antigen receptor complex-associated protein
• UniProt Gene Name: CD79A
• UniProt Synonym Gene Names: IGA; MB1
• UniProt Entry Name: CD79A_HUMAN

NCBI Description

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; lipid raft; external side of plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation

Disease: Agammaglobulinemia 3, Autosomal Recessive