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Immunohistochemistry (IHC) (Immunohistochemistry staining of rat liver, with induced hepatocellular damage, using C2423-05N1.)

Mouse anti-Bovine, Rat CD68 Monoclonal Antibody | anti-CD68 antibody

CD68 (DKFZp686M18236, GP110, Macrophage Antigen CD68 (Microsialin), Macrosialin, Scavenger Receptor Class D Member 1, SCARD1) (MaxLight 405)

Reactivity
Bovine, Rat
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Purified by protein A affinity chromatography from tissue culture supernatant.
Synonyms
CD68; Monoclonal Antibody; CD68 (DKFZp686M18236; GP110; Macrophage Antigen CD68 (Microsialin); Macrosialin; Scavenger Receptor Class D Member 1; SCARD1) (MaxLight 405); CD68 Antigen; CD68 Molecule; Monocytes/Macrophages; anti-CD68 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Bovine, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10B1909
Specificity
Recognizes rat CD68 at ~90-110kD. Species crossreactivity: bovine. Does not react with equine.
Purity/Purification
Purified by protein A affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight405.
Applicable Applications for anti-CD68 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Rat spleen cells
Conjugate
MaxLight405
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry staining of rat liver, with induced hepatocellular damage, using C2423-05N1.)

Immunohistochemistry (IHC) (Immunohistochemistry staining of rat liver, with induced hepatocellular damage, using C2423-05N1.)

Testing Data

(Immunoperoxidase staining of rat lymph node cryosection using C2423-05N1 followed by horseradish peroxidase conjugated goat anti-mouse IgG1 as a detection reagent. High power)

Testing Data (Immunoperoxidase staining of rat lymph node cryosection using C2423-05N1 followed by horseradish peroxidase conjugated goat anti-mouse IgG1 as a detection reagent. High power)

Immunofluorescence (IF)

(Immunofluorescence staining of rat lymph node cryosection using C2423-05N1, red in A and mouse anti-rat CD4 (C2255-04D), green in B. C is the merged image with nuclei counter-stained blue using DAPI. Low power)

Immunofluorescence (IF) (Immunofluorescence staining of rat lymph node cryosection using C2423-05N1, red in A and mouse anti-rat CD4 (C2255-04D), green in B. C is the merged image with nuclei counter-stained blue using DAPI. Low power)
Product Categories/Family for anti-CD68 antibody
References
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(2013) Beneficial Effects of Cod Protein on Inflammatory Cell Accumulation in Rat Skeletal Muscle after Injury Are Driven by Its High Levels of Arginine, Glycine, Taurine and Lysine. PLoS One. 8: e77274. 22. Machelska, H. et al. (2004) Selectins and integrins but not platelet-endothelial cell adhesion molecule-1 regulate opioid inhibition of inflammatory pain. Br J Pharmacol. 142 (4): 772-80. 23. Chang, C.Y. et al. (2013) Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. J Nutr Biochem. 24 (12): 2127-37. 24. Sakuraya, K. et al. (2014) The synergistic effect of mizoribine and a direct renin inhibitor, aliskiren, on unilateral ureteral obstruction induced renal fibrosis in rats. J Urol. 191 (4): 1139-46. 25. Xu, X. et al. (2014) Aging aggravates long-term renal ischemia-reperfusion injury in a rat model. J Surg Res. 187 (1): 289-96. 26. Kim, Y.H. et al. 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(2016) Interleukin-6 inhibition attenuates hypertension and associated renal damage in Dahl salt-sensitive rats. Am J Physiol Renal Physiol. 311 (3): F555-61. 44. Cha, S.J. et al. (2016) Identification of GAPDH on the surface of Plasmodium sporozoites as a new candidate for targeting malaria liver invasion. J Exp Med. 213 (10): 2099-112. 45. Murata, M. et al. (2016) Surfactant protein D is a useful biomarker for monitoring acute lung injury in rats. Exp Lung Res. 42 (6): 314-21. 46. Faleiros, C.M. et al. (2016) Effects of previous physical training on adriamycin nephropathy and its relationship with endothelial lesions and angiogenesis in the renal cortex. Life Sci. pii: S0024-3205(16)30665-8. 47. Haba, D. et al. (2017) Morphological study on the pressure ulcer-like dermal lesions formed in the rat heel skin after transection of the sciatic nerves. Acta Histochem. 119 (1): 39-47. 48. Landeck, N. et al. (2016) Toxic effects of human and rodent variants of alpha-synuclein in vivo. Eur J Neurosci. Nov 28. 49. Carrillo-de Sauvage MA et al. (2015) The neuroprotective agent CNTF decreases neuronal metabolites in the rat striatum: an in vivo multimodal magnetic resonance imaging study. J Cereb Blood Flow Metab. 35 (6): 917-21. 50. Chang, C.Y. et al. (2015) Tetramethylpyrazine inhibits neutrophil activation following permanent cerebral ischemia in rats. Biochem Biophys Res Commun. 463 (3): 421-7. 51. Londono, R. et al. (2017) The Effect of Cell Debris within Biologic Scaffolds upon the Macrophage Response. J Biomed Mater Res A. Mar 6. 52. Xue, Y. et al. (2017) Hydroxyapatite nanoparticle-induced mitochondrial energy metabolism impairment in liver cells: in vitro and in vivo studies. J Appl Toxicol. Mar 6. 53. Wang, M. et al. (2017) Characterization of the Micro-Environment of the Testis that Shapes the Phenotype and Function of Testicular Macrophages. J Immunol. May 1. pii: 1700162. 54. Menzies, R.I. et al. (2015) Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats. Kidney Int. 88 (5): 1079-87. 55. Aarts, S.A.B.M. et al. (2017) Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. J Neuroinflammation. 14 (1): 105. 56. Han, T.T. et al. (2015) Adipose-derived stromal cells mediate in vivo adipogenesis, angiogenesis and inflammation in decellularized adipose tissue bioscaffolds. Biomaterials. 72: 125-37. 57. Kanamori, H. et al. (2017) Influence of nicotine on choline-deficient, L-amino acid-defined diet-induced non-alcoholic steatohepatitis in rats. PLoS One. 12 (6): e0180475. 58. Kühne, L. et al. (2017) Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy. BMC Immunol. 18 (1): 52. 59. Jaworska, J. et al. 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NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
macrosialin
NCBI Official Synonym Full Names
Cd68 molecule
NCBI Official Symbol
Cd68
NCBI Protein Information
macrosialin; CD68 antigen
UniProt Protein Name
Cd68 molecule
Protein Family
UniProt Gene Name
Cd68
UniProt Entry Name
Q4FZY1_RAT

Research Articles on CD68

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Product Notes

The CD68 cd68 (Catalog #AAA6252641) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD68 (DKFZp686M18236, GP110, Macrophage Antigen CD68 (Microsialin), Macrosialin, Scavenger Receptor Class D Member 1, SCARD1) (MaxLight 405) reacts with Bovine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD68 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the CD68 cd68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD68, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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