Flow Cytometry (FC/FACS)
(Flow cytometry analysis (surface staining) of murine splenocytes using anti-mouse CD45R (RA3-6B2)APC antibody (red, concentration in sample 1 ug/ml) with blank sample (blue).)
Rat CD45R Monoclonal Antibody | anti-CD45R antibody
Anti-Ms CD45R APC
Reactivity
Cat, Mouse, Human
Applications
Flow Cytometry, Functional Assay
Purity
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Synonyms
CD45R; Monoclonal Antibody; Anti-Ms CD45R APC; PTPRCR; T200R; anti-CD45R antibody
Host
Rat
Reactivity
Cat, Mouse, Human
Clonality
Monoclonal
Isotype
IgG2a kappa
Clone Number
RA3-6B2
Specificity
The rat monoclonal antibody RA3-6B2 recognizes an extracellular epitope on CD45R, which is expressed at all developmental stages of B cells, including activated B cells, but also on subsets of NK and T cells. T cells detected by this antibody are supposed to be in activated state.
Purity/Purification
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
0.5 mg/ml (varies by lot)
Applicable Applications for anti-CD45R antibody
Flow Cytometry (FC/FACS)
Application Notes
FC/FACS: QC tested
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Conjugation
APC
Preparation and Storage
Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.
Flow Cytometry (FC/FACS)
(Flow cytometry analysis (surface staining) of murine splenocytes using anti-mouse CD45R (RA3-6B2)APC antibody (red, concentration in sample 1 ug/ml) with blank sample (blue).)
Flow Cytometry (FC/FACS)
(Flow cytometry analysis (surface staining) of murine splenocytes using anti-mouse CD45R (RA3-6B2)APC antibody (red, concentration in sample 1 ug/ml) with blank sample (blue).)
Related Product Information for anti-CD45R antibody
CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
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Product Notes
The CD45R (Catalog #AAA1801509) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Ms CD45R APC reacts with Cat, Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD45R can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FACS: QC tested. Researchers should empirically determine the suitability of the CD45R for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD45R, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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