CD34 recombinant antibody
Anti-CD34 [My10]
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation, Immunohistochemistry
Purity
PurifiedProtein A Affinity Purified
Synonyms
CD34; Monoclonal Recombinant Antibody; Anti-CD34 [My10]; Hematopoietic progenitor cell antigen CD34; CD34 recombinant antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1, kappa
Clone Number
My10
Specificity
Human CD34, an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on thesurface of most human hematopoietic stem and progenitor cells (HSPCs) as well as on mesenchymalstem cells, embryonic fibroblasts, endothelial cells, neurons, and some tumor cell lines.
Purity/Purification
Purified
Protein A Affinity Purified
Protein A Affinity Purified
Sequence Length
328
Applicable Applications for CD34 recombinant antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Immunogen
KG-1a Human myeloblastic leukemic cell line (immature human myeloid cell line)from a patient with nonlymphocytic leukemia.
Antigen
CD34
Antigen Description
KG-1a Human myeloblastic leukemic cell line (immature human myeloid cell line) from a patient with nonlymphocytic leukemia.
Buffer Composition
PBS only with 0.02% Proclin 300.
Publication Note
Describes the making of the antibody,shows it recognised ~115kDa My10 protein using immunoprecipitation and flow cytometry.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for CD34 recombinant antibody
Recombinant monoclonal antibody to CD34. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the hybridoma My10.
Product Categories/Family for CD34 recombinant antibody
References
Civin CI, Strauss LC, Brovall C, Fackler MJ, Schwartz JF, Shaper JH. J Immunol. 1984Jul;133(1):157-65. PMID:6586833
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
35,011 Da
NCBI Official Full Name
CD34
NCBI Official Synonym Full Names
CD34 molecule
NCBI Official Symbol
CD34
NCBI Protein Information
hematopoietic progenitor cell antigen CD34
UniProt Protein Name
Hematopoietic progenitor cell antigen CD34
Protein Family
UniProt Gene Name
CD34
NCBI Description
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Research Articles on CD34
Similar Products
Product Notes
The CD34 cd34 (Catalog #AAA488219) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD34 [My10] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD34 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CD34 cd34 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD34, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
