Western Blot (WB)
(Western Blot analysis of Rat brain tissue using PARD3A Polyclonal Antibody at dilution of 1:500)
Rabbit anti-Rat PARD3 Polyclonal Antibody | anti-PARD3 antibody
PARD3 Polyclonal Antibody
Gene Names
Pard3; Par3
Reactivity
Rat
Applications
Western Blot
Purity
Affinity Purification
Synonyms
PARD3; Polyclonal Antibody; PARD3 Polyclonal Antibody; agouti signaling protein; ASIP; Atypical PKC isotype specific interacting protein; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; Coagulation factor II receptor-like 2; CTCL tumor antigen se2-5; F2rl2; PAR-3; par-3 family cell polarity regulator alpha; par-3 family cell polarity regulator; PAR3 alpha; par3; PAR3-alpha; PARD-3; Pard3; PARD3A; Partitioning defective 3 homolog; Partitioning-defective 3 homolog; Partitioning-defective protein 3; C. elegans; homolog of; SE2-5L16; SE2-5LT1; SE2-5T2; Thrombin receptor-like 2; anti-PARD3 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
2 mg/mL (varies by lot)
Sequence Length
1,033
Applicable Applications for anti-PARD3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant Rat Partitioning defective 3 homolog protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of Rat brain tissue using PARD3A Polyclonal Antibody at dilution of 1:500)
Western Blot (WB)
(Western Blot analysis of Rat brain tissue using PARD3A Polyclonal Antibody at dilution of 1:500)
Related Product Information for anti-PARD3 antibody
This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.PARD3 (Par-3 Family Cell Polarity Regulator) is a Protein Coding gene. Diseases associated with PARD3 include Gamma Heavy Chain Disease and Enamel Caries. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Ras signaling pathway. GO annotations related to this gene include protein phosphatase binding and phosphatidylinositol-4, 5-bisphosphate binding. An important paralog of this gene is PARD3B.
Product Categories/Family for anti-PARD3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 151 kDa
Observed: 151 kDa
Observed: 151 kDa
NCBI Official Full Name
partitioning defective 3 homolog
NCBI Official Synonym Full Names
par-3 family cell polarity regulator
NCBI Official Symbol
Pard3
NCBI Official Synonym Symbols
Par3
NCBI Protein Information
partitioning defective 3 homolog
UniProt Protein Name
Partitioning defective 3 homolog
Protein Family
UniProt Gene Name
Pard3
UniProt Synonym Gene Names
Par3; PAR-3; PARD-3; ASIP; ASBP
NCBI Description
may mediate the establishment and maintenance of epithelial cell polarity [RGD, Feb 2006]
Uniprot Description
Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:18550519). Seems to play a central role in the formation of epithelial tight junctions (). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (). Involved in Schwann cell peripheral myelination (PubMed:21949390). Targets the phosphatase PTEN to cell junctions (PubMed:18082612).
Research Articles on PARD3
Similar Products
Product Notes
The PARD3 pard3 (Catalog #AAA2554028) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARD3 Polyclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PARD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PARD3 pard3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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