Testing Data
(Immunohistochemical staining of rat spleen cryosection with Mouse anti Rat CD31 (MBS212104))
Mouse CD31 Monoclonal Antibody | anti-CD31 antibody
MOUSE ANTI RAT CD31:FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Flow Cytometry: Maximum Dilution: Neat
1% Bovine Serum Albumin
Preparation
Shelf Life: 18 months from date of despatch.
Testing Data
(Immunohistochemical staining of rat spleen cryosection with Mouse anti Rat CD31 (MBS212104))
Testing Data
(Immunohistochemical staining of rat spleen cryosection with Mouse anti Rat CD31 (MBS212104))
Testing Data
(Immunohistochemical staining of rat brain cryosection with Mouse anti Rat CD31 (MBS212105))
Testing Data
(Immunohistochemical staining of rat brain cryosection with Mouse anti Rat CD31 (MBS212105))
NCBI and Uniprot Product Information
NCBI Description
cell adhesion molecule, also intracellular signaling molecule; may mediate leukocyte adhesion and migration, angiogenesis, and thrombosis [RGD, Feb 2006]
Uniprot Description
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Protein type: Membrane protein, integral; Cell adhesion; G protein, monomeric, non-Rab; Cell surface; Contractile; Motility/polarity/chemotaxis; Vesicle
Cellular Component: extracellular space; cell surface; smooth muscle contractile fiber; membrane; plasma membrane; integral to membrane; intracellular; cell junction; external side of plasma membrane; lipid raft
Molecular Function: protein binding
Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; wound healing; positive regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of actin filament polymerization; response to cytokine stimulus; diapedesis; positive regulation of leukocyte migration; cell adhesion; regulation of cell migration; phagocytosis; Rho protein signal transduction
Research Articles on CD31
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Product Notes
The CD31 pecam1 (Catalog #AAA210658) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD31 can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Maximum Dilution: Neat. Researchers should empirically determine the suitability of the CD31 pecam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD31, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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