Flow Cytometry (FC/FACS)
(C57BL/6 murine splenocytes are stained with Anti-Mouse CD3 Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.)
Rat anti-Mouse CD3 Monoclonal Antibody | anti-CD3 antibody
Anti-Mouse CD3 Monoclonal Antibody (PerCP/Cy5.5 Conjugated)
Gene Names
Cd3d; T3d
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
CD3; Monoclonal Antibody; Anti-Mouse CD3 Monoclonal Antibody (PerCP/Cy5.5 Conjugated); T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain; CD3E/D/G/Z; CD3e/d/g/z; anti-CD3 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
17A2
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Sequence Length
173
Applicable Applications for anti-CD3 antibody
Flow Cytometry (FC/FACS)
Conjugation
PerCP/Cy5.5
Preparation and Storage
Store at 2-8 degree C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry (FC/FACS)
(C57BL/6 murine splenocytes are stained with Anti-Mouse CD3 Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.)
Flow Cytometry (FC/FACS)
(C57BL/6 murine splenocytes are stained with Anti-Mouse CD3 Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.)
Related Product Information for anti-CD3 antibody
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3epsilon, delta, gamma and zeta chains. It forms a TCR complex by associating with TCR alpha/beta or gamma/delta chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
References
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Davis MM. 1990. Annu. Rev. Biochem. 59:475. 3. Weiss A, et al. 1994. Cell 76:263.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
T-cell surface glycoprotein CD3 delta chain
NCBI Official Synonym Full Names
CD3 antigen, delta polypeptide
NCBI Official Symbol
Cd3d
NCBI Official Synonym Symbols
T3d
NCBI Protein Information
T-cell surface glycoprotein CD3 delta chain
UniProt Protein Name
T-cell surface glycoprotein CD3 delta chain
Protein Family
UniProt Gene Name
Cd3d
UniProt Synonym Gene Names
T3d
UniProt Entry Name
CD3D_MOUSE
Uniprot Description
CD3D: a T cell surface glycoprotein that is a component of the T cell antigen receptor. A defect in this protein causes a severe combined immunodeficiency characterized by the absence of T cells but normal B cells. Contains 1 ITAM domain.
Protein type: Receptor, misc.; Membrane protein, integral
Cellular Component: T cell receptor complex; membrane; integral to membrane; alpha-beta T cell receptor complex
Molecular Function: protein binding; transmembrane receptor activity; protein heterodimerization activity
Biological Process: cell surface receptor linked signal transduction; T cell activation; protein complex assembly; positive thymic T cell selection
Research Articles on CD3
Similar Products
Product Notes
The CD3 cd3d (Catalog #AAA2556830) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD3 Monoclonal Antibody (PerCP/Cy5.5 Conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD3 cd3d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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