Testing Data
(Analysis of CD226 expression on spleen lymphocytes.)
Rabbit anti-Mouse CD226 Monoclonal Antibody | anti-CD226 antibody
Recombinant Anti-CD226 Antibody (PE), Rabbit Monoclonal
Gene Names
Cd226; Pta1; DNAM1; DNAM-1; TLiSA1; BC051526
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
CD226; Monoclonal Antibody; Recombinant Anti-CD226 Antibody (PE); Rabbit Monoclonal; CD226/DNAM-1 Antibody (PE); Rabbit MAb; CD226 molecule; Anti-BC051526 Antibody; Anti-DNAM-1 Antibody; Anti-DNAM1 Antibody; Anti-Pta1 Antibody; Anti-TLiSA1 Antibody; anti-CD226 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
026
Specificity
Mouse CD226/DNAM-1
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
10ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-CD226 antibody
Flow Cytometry (FC/FACS/FCM)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse CD226/DNAM-1 protein
Conjugation
PE
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD226/DNAM-1 (rM CD226/DNAM-1) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Testing Data
(Analysis of CD226 expression on spleen lymphocytes.)
Testing Data
(Analysis of CD226 expression on spleen lymphocytes.)
Related Product Information for anti-CD226 antibody
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.
Product Categories/Family for anti-CD226 antibody
References
Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,063 Da
NCBI Official Full Name
CD226 antigen isoform a
NCBI Official Synonym Full Names
CD226 antigen
NCBI Official Symbol
Cd226
NCBI Official Synonym Symbols
Pta1; DNAM1; DNAM-1; TLiSA1; BC051526
NCBI Protein Information
CD226 antigen; platelet and T cell activation antigen 1; platelet and T-cell activation antigen 1
UniProt Protein Name
CD226 antigen
Protein Family
UniProt Gene Name
Cd226
UniProt Synonym Gene Names
Pta1
UniProt Entry Name
CD226_MOUSE
Uniprot Description
DNAM-1: Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.
Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion
Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane
Molecular Function: integrin binding; protein binding; cell adhesion molecule binding; protein kinase binding
Biological Process: positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; cytokine production; positive regulation of natural killer cell mediated cytotoxicity; cell adhesion; positive regulation of mast cell activation
Research Articles on CD226
Similar Products
Product Notes
The CD226 cd226 (Catalog #AAA8111239) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-CD226 Antibody (PE), Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD226 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the CD226 cd226 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD226, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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