Rat anti-Mouse CD210 Monoclonal Antibody | anti-CD210 antibody
AF/LE Purified Anti-Mouse CD210 Monoclonal Antibody
Gene Names
Il10ra; Il10r; CDw210; CDw210a; IL-10R1; IL-10RA; mIL-10R; AW553859
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Western Blot
Synonyms
CD210; Monoclonal Antibody; AF/LE Purified Anti-Mouse CD210 Monoclonal Antibody; Interleukin-10 receptor subunit alpha; Il10ra; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; anti-CD210 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
1B1.3A
Form/Format
0.2 mum filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives.
Concentration
0.5 mg/mL (varies by lot)
Sequence Length
575
Applicable Applications for anti-CD210 antibody
Flow Cytometry (FC/FACS), Western Blot (WB), Block
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <= 0.25 ug per 106 cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Conjugation
None (Purified antibody, Low endotoxin/Azide Free)
Endotoxin
Endotoxin level is < 2 EU/mg (< 0.002EU/mug) as Determined by LAL gel clotting assay.
Preparation and Storage
Store at 2-8 degree C. Do not freeze.
Related Product Information for anti-CD210 antibody
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
interleukin-10 receptor subunit alpha isoform 1
NCBI Official Synonym Full Names
interleukin 10 receptor, alpha
NCBI Official Symbol
Il10ra
NCBI Official Synonym Symbols
Il10r; CDw210; CDw210a; IL-10R1; IL-10RA; mIL-10R; AW553859
NCBI Protein Information
interleukin-10 receptor subunit alpha
UniProt Protein Name
Interleukin-10 receptor subunit alpha
UniProt Gene Name
Il10ra
UniProt Synonym Gene Names
Il10r; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R1
UniProt Entry Name
I10R1_MOUSE
Uniprot Description
IL10RA: a receptor for interleukin 10 structurally related to interferon receptors. Mediates the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Protein type: Receptor, cytokine; Membrane protein, integral
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: interleukin-10 binding; interleukin-10 receptor activity
Biological Process: cytokine and chemokine mediated signaling pathway
Research Articles on CD210
Similar Products
Product Notes
The CD210 il10ra (Catalog #AAA2558279) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The AF/LE Purified Anti-Mouse CD210 Monoclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD210 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB), Block. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <= 0.25 ug per 106 cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Researchers should empirically determine the suitability of the CD210 il10ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD210, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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