Goat APOL2 Polyclonal Antibody | anti-APOL2 antibody

Goat anti-APOL2 Antibody

Cat. Num. AAA422101

• Gene Names: APOL2; APOL3; APOL-II
• Reactivity: Tested: Human; Expected from sequence similarity: Human
• Applications: ELISA, Western Blot
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: APOL2; Polyclonal Antibody; Goat anti-APOL2 Antibody; apolipoprotein L; 2; APOL-II; OTTHUMP00000028936; apolipoprotein L-II; apolipoprotein L2; APOL2 antibody; 2 antibody; APOL-II antibody; OTTHUMP00000028936 antibody; apolipoprotein L-II antibody; apolipoprotein L2 antibody; anti-APOL2 antibody

• Host: Goat
• Reactivity: Tested: Human; Expected from sequence similarity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: TKIHEMLQPGQD
• Sequence Length: 337

• Applicable Applications for anti-APOL2 antibody: Peptide ELISA (EIA), Western Blot (WB)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 64000.; Western Blot: Approx.37.1kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 38kDa according to NP_112092.1; NP_663612.1). Recommended concentration: 0. 03-0.1ug/ml.
• Immunogen: Peptide with sequence C-TKIHEMLQPGQD, from the C Terminus of the protein sequence according to NP_112092.1; NP_663612.1.
• Epitope: C Terminus
• Note: Both reported isoforms represent identical proteins (NP_112092.1; NP_663612.1).
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

((0. 03ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

• NCBI GI #: 13562090
• NCBI GeneID: 23780
• NCBI Accession #: NP_112092.1; NP_663612.1
• NCBI GenBank Nucleotide #: NM_030882.2
• Molecular Weight: 37,092 Da
• NCBI Official Full Name: apolipoprotein L2
• NCBI Official Synonym Full Names: apolipoprotein L2
• NCBI Official Symbol: APOL2
• NCBI Official Synonym Symbols: APOL3; APOL-II
• NCBI Protein Information: apolipoprotein L2
• UniProt Protein Name: Apolipoprotein L2
• Protein Family: Apolipoprotein
• UniProt Gene Name: APOL2
• UniProt Synonym Gene Names: ApoL-II
• UniProt Entry Name: APOL2_HUMAN

NCBI Description

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

APOL2: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. Belongs to the apolipoprotein L family.

Chromosomal Location of Human Ortholog: 22q12

Cellular Component: endoplasmic reticulum membrane; extracellular region; membrane

Molecular Function: high-density lipoprotein binding; lipid binding; receptor binding

Biological Process: acute-phase response; cholesterol metabolic process; lipid metabolic process; lipid transport; lipoprotein metabolic process; maternal process involved in pregnancy; multicellular organismal development

Disease: Schizophrenia