Flow Cytometry (FC/FACS)
(Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD3 (UCHT1) PE antibody (20 ul reagent / 100 ul of peripheral whole blood) and anti-human CD200 (OX-104) purified antibody (concentration in sample 4 ug/ml) GAM APC.)
Mouse anti-Human CD200 Monoclonal Antibody | anti-CD200 antibody
Anti-Hu CD200 Purified
Gene Names
CD200; MRC; MOX1; MOX2; OX-2
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
CD200; Monoclonal Antibody; Anti-Hu CD200 Purified; CD200 molecule; MRC; MOX; OX-2; anti-CD200 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
OX-104
Specificity
The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
278
Applicable Applications for anti-CD200 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Frozen/Paraffin
Application Notes
FC/FACS: QC tested
Immunogen
Human CD200
Preparation and Storage
Store at 2-8 degree C.
Flow Cytometry (FC/FACS)
(Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD3 (UCHT1) PE antibody (20 ul reagent / 100 ul of peripheral whole blood) and anti-human CD200 (OX-104) purified antibody (concentration in sample 4 ug/ml) GAM APC.)
Flow Cytometry (FC/FACS)
(Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD3 (UCHT1) PE antibody (20 ul reagent / 100 ul of peripheral whole blood) and anti-human CD200 (OX-104) purified antibody (concentration in sample 4 ug/ml) GAM APC.)
Related Product Information for anti-CD200 antibody
CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
OX-2 membrane glycoprotein
NCBI Official Synonym Full Names
CD200 molecule
NCBI Official Symbol
CD200
NCBI Official Synonym Symbols
MRC; MOX1; MOX2; OX-2
NCBI Protein Information
OX-2 membrane glycoprotein
UniProt Protein Name
OX-2 membrane glycoprotein
Protein Family
UniProt Gene Name
CD200
UniProt Synonym Gene Names
MOX1; MOX2
NCBI Description
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Uniprot Description
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Research Articles on CD200
Similar Products
Product Notes
The CD200 cd200 (Catalog #AAA1801430) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hu CD200 Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD200 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Frozen/Paraffin. FC/FACS: QC tested. Researchers should empirically determine the suitability of the CD200 cd200 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD200, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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