Flow Cytometry (FC/FACS)
(Staining of unstimulated (left) and 3-day ConA stimulated (right) rat splenocytes with CD278 antibody (FITC) and 0.5 ug of CD152 antibody (PE). Total viable cells were used for analysis.)
Mouse anti-Rat CD152 Monoclonal Antibody | anti-CD152 antibody
CD152 antibody (PE)
Reactivity
Rat
Applications
Flow Cytometry, Functional Assay
Synonyms
CD152; Monoclonal Antibody; CD152 antibody (PE); Mouse monoclonal CD152 antibody (PE); Monoclonal CD152 antibody; Anti-CD152 antibody; CD-152 antibody; Ly-56 antibody; CD-152; CD 152 antibody; CD 152; CTLA4 antibody; anti-CD152 antibody
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
WKH203
Specificity
Rat
Form/Format
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration
5 ul (1 ug)/test (varies by lot)
Applicable Applications for anti-CD152 antibody
Flow Cytometry (FC/FACS)
Application Notes
FC/FACS: 5 ul (1 ug)/test
A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test.
A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test.
Conjugate
PE
Preparation and Storage
Store at 2-8 degree C. Do not freeze. Protect from light.
Flow Cytometry (FC/FACS)
(Staining of unstimulated (left) and 3-day ConA stimulated (right) rat splenocytes with CD278 antibody (FITC) and 0.5 ug of CD152 antibody (PE). Total viable cells were used for analysis.)
Flow Cytometry (FC/FACS)
(Staining of unstimulated (left) and 3-day ConA stimulated (right) rat splenocytes with CD278 antibody (FITC) and 0.5 ug of CD152 antibody (PE). Total viable cells were used for analysis.)
Related Product Information for anti-CD152 antibody
The WKH203 monoclonal antibody reacts with rat CD152, also known as the cytotoxic T lymphocyte antigen-4. CTLA-4, a protein with structural similarities to CD28, is expressed on activated T cells and binds the B7 family members, CD80 and CD86, with higher affinity than CD28 does. CTLA-4 and CD28 appear to deliver opposing signals to T cells: while CD28 is a potent costimulator, CTLA-4 restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. The cytoplasmic portion of CTLA-4 contains ER retention motifs, resulting in intracellular localization of a large proportion of newly synthesized CTLA-4 in response to TCR signaling.
Product Categories/Family for anti-CD152 antibody
Similar Products
Product Notes
The CD152 (Catalog #AAA5309386) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD152 antibody (PE) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD152 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FACS: 5 ul (1 ug)/test A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. Researchers should empirically determine the suitability of the CD152 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD152, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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