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Testing Data

Mouse anti-Human CD152 Monoclonal Antibody | anti-CD152 antibody

Anti-Human CD152 (CTLA-4) Antibody

Reactivity
Human
Applications
Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Protein A Purified
Synonyms
CD152; Monoclonal Antibody; Anti-Human CD152 (CTLA-4) Antibody; anti-CD152 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1kappa
Specificity
Antibody ANC152.2 reacts with CTLA-4 expressed on activated T cells
Purity/Purification
Protein A Purified
Form/Format
Liquid; PBS, pH 7.4 with 0.02% Sodium Azide.
Concentration
1ug/ul (varies by lot)
Applicable Applications for anti-CD152 antibody
Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro.
Immunogen
Stimulated human PBL's and human CD152 Ig fusion protein
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Testing Data
Related Product Information for anti-CD152 antibody
mAb name/Clone: ANC152.2/8H5Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Antibody ANC152.2 binds to CTLA-4 expressed on activated T cells. ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor.

Similar Products

Product Notes

The CD152 (Catalog #AAA4159599) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human CD152 (CTLA-4) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD152 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Flow Cytometry (FC/FACS). ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. Researchers should empirically determine the suitability of the CD152 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD152, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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