Rabbit anti-Human CD124/IL4R  Monoclonal Antibody | anti-CD124/IL4R  antibody

Rabbit anti Human CD124/IL4R  Monoclonal Antibody

Cat. Num. AAA2543976

• Reactivity: Human
• Applications: ELISA
• Synonyms: CD124/IL4R ; Monoclonal Antibody; Rabbit anti Human CD124/IL4R Monoclonal Antibody; anti-CD124/IL4R antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG

• Applicable Applications for anti-CD124/IL4R antibody: ELISA (EIA)
• Application Notes: ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human IL4R. The detection limit for Human IL4R is 0.00975 ng/well.
• Immunogen: Recombinant Human IL4R protein
• Buffer: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL4R (rh IL4R; NP_000409.1; Met 1-His 232).
• Preparation and Storage: This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -70 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Related Product Information for anti-CD124/IL4R  antibody

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD124, also known as interleukin 4 receptor (IL4R), is a typeI transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.