Mouse anti-Human CCNK Monoclonal Antibody | anti-CCNK antibody
CCNK (Cyclin K, Cyclin-K, CPR4, MGC9113) (AP)
Western Blot (WB)
(Western Blot analysis of CCNK expression in transfected 293T cell line by CCNK monoclonal antibody Lane 1: CCNK transfected lysate (41kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western blot analysis of CCNK over-expressed 293 cell line, cotransfected with CCNK Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with CCNK monoclonal antibody GAPDH (36.1kD) used as specificity and loading control.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: May play a role in transcriptional regulation. In vitro, is associated with a kinase activity toward both RNA polymerase II C-terminal domain and CDK2 (CAK). Ref.9
Subunit structure: Part of a cyclin-kinase pair in the RNA polymerase II holoenzyme. Binds to CDK9.
Tissue specificity: Ubiquitously expressed. Highest levels in testis.
Sequence similarities: Belongs to the cyclin family. Cyclin C subfamily.
Research Articles on CCNK
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Product Notes
The CCNK ccnk (Catalog #AAA6130409) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CCNK (Cyclin K, Cyclin-K, CPR4, MGC9113) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCNK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CCNK ccnk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCNK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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