ELISA (EIA)
(Sandwich ELISA analysis of human CCL8 using Mouse anti Human CCL8 as a capture reagent and biotinylated Mouse anti Human CCL8 (MBS226098) as a detection reagent with purified recombinant CCL8 as the antigen. Detection was performed using HRP co)
Mouse anti-Human CCL8 Monoclonal Antibody | anti-CCL8 antibody
Mouse anti Human CCL8:Biotin
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Purified IgG conjugated to Biotin - liquid
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
ELISA (EIA)
(Sandwich ELISA analysis of human CCL8 using Mouse anti Human CCL8 as a capture reagent and biotinylated Mouse anti Human CCL8 (MBS226098) as a detection reagent with purified recombinant CCL8 as the antigen. Detection was performed using HRP co)
ELISA (EIA)
(Sandwich ELISA analysis of human CCL8 using Mouse anti Human CCL8 as a capture reagent and biotinylated Mouse anti Human CCL8 (MBS226098) as a detection reagent with purified recombinant CCL8 as the antigen. Detection was performed using HRP co)
The biotinylated Mouse anti Human CCL8 antibody, clone E09-8A1 can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL8 antibody, clone E07-8G5 as the capture antibody.
NCBI and Uniprot Product Information
NCBI Description
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
Uniprot Description
CCL8: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: extracellular space
Molecular Function: heparin binding; chemokine activity; protein kinase activity; phospholipase activator activity
Biological Process: cellular calcium ion homeostasis; positive regulation of catalytic activity; exocytosis; cell-cell signaling; calcium ion transport; response to virus; immune response; chemotaxis; inflammatory response; signal transduction; protein amino acid phosphorylation
Research Articles on CCL8
Similar Products
Product Notes
The CCL8 ccl8 (Catalog #AAA226098) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti Human CCL8:Biotin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCL8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1.0ug/ml. Researchers should empirically determine the suitability of the CCL8 ccl8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCL8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
