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Western Blot (WB)

Mouse anti-Human C1s Monoclonal Antibody | anti-C1S antibody

C1s Mouse mAb

Gene Names
C1S; EDSPD2
Reactivity
Human
Applications
Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Synonyms
C1s; Monoclonal Antibody; C1s Mouse mAb; anti-C1S antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Sequence Length
521
Applicable Applications for anti-C1S antibody
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:1000-1:5000
IP: 10 tests
FC/FACS: 1:100-1:200
Source Note
This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of C1s
Preparation and Storage
Store at -20 degree C. Stable for one year from the date of shipment.

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-C1S antibody
C1s (Complement component 1S) is a protein that in humans is encoded by the C1S gene. It is inhibited by SERPING1. C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. The protein cleaves C4, which eventually leads to the production of the C4b-C2a form of C3-convertase.
Product Categories/Family for anti-C1S antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
716
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted MW: 84kDa
NCBI Official Full Name
complement C1s subcomponent isoform 2
NCBI Official Synonym Full Names
complement C1s
NCBI Official Symbol
C1S
NCBI Official Synonym Symbols
EDSPD2
NCBI Protein Information
complement C1s subcomponent
UniProt Protein Name
Complement C1s subcomponent
UniProt Gene Name
C1S

NCBI Description

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]

Uniprot Description

C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

Research Articles on C1S

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Product Notes

The C1S c1s (Catalog #AAA435465) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The C1s Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C1s can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). WB: 1:1000-1:5000 IP: 10 tests FC/FACS: 1:100-1:200. Researchers should empirically determine the suitability of the C1S c1s for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C1s, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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