Mouse anti-Human C-Reactive Protein (CRP) Monoclonal Antibody | anti-CRP antibody

C-Reactive Protein (CRP): Human, Mouse monoclonal (Antibody) Clone 8G1

Cat. Num. AAA398044

• Gene Names: CRP; PTX1
• Reactivity: Human
• Applications: ELISA
• Purity: Affinity chromatography on a column with immobilized protein G
• Synonyms: C-Reactive Protein (CRP); Monoclonal Antibody; C-Reactive Protein (CRP): Human; Mouse monoclonal (Antibody) Clone 8G1; C-reactive protein (CRP); Human C-Reactive Protein (CRP) Mouse Monoclonal Antibody; clone: 8G1; anti-CRP antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Mouse IgG
• Clone Number: 8G1
• Purity/Purification: Affinity chromatography on a column with immobilized protein G
• Form/Format: Solution in PBS
• Sequence Length: 26

• Applicable Applications for anti-CRP antibody: ELISA (EIA) capture
• Application Notes: This antibody can be used as a capture antibody in a human C-Reactive Protein ELISA in combination with monoclonal anti-human CRP antibody.
• Immunogen: E Coli derived recombinant human C-Reactive Protein (CRP)
• Preparation and Storage: Store at -20 degree C.

Related Product Information for anti-CRP antibody

C-reactive protein (CRP) is a circulating protein mainly secreted from the liver. This acute phase protein consists of five identical non-glycosylated subunits of 23 kDa, that give rise to a symmetrically arranged globular protein with molecular weight of approximately 120 kDa. It has long been recognized that CRP is closely related to immunology, inflammation and host defence; as a result it has been used as an inflammatory marker. However, the development of high-sensitivity CRP (hsCRP) ELISA had addressed its role in other clinical issues. There is accumulating evidence suggesting the important role that CRP plays in mediating cardiovascular diseases (CVD) and type 2 diabetes. Normally CRP is presenting only in a trace amount in circulation (<1 mg/ml) but can increase over 1,000-fold under acute inflammatory state. Individuals with blood CRP levels <1 mg/ml, 1-3 mg/ml and >3 mg/ml are considered to have low, moderate and high risk, respectively, of CVD and myocardial infraction. Therefore, blood CRP level has become a promising biomarker for CVD risk.

References

1. Should C-reactive protein be a target of therapy Oh J, Teoh H, Leiter LA. Diabetes Care. 2011 May;34 Suppl 2:S155-60.
2. High-sensitivity C-reactive protein and cardiovascular disease: a resolute belief or an elusive link Yousuf O, et al. J Am Coll Cardiol. 2013 Jul 30;62(5):397-408

NCBI and Uniprot Product Information

• NCBI GI #: 181073
• NCBI GeneID: 1401
• NCBI Official Full Name: C-reactive protein, partial
• NCBI Official Synonym Full Names: C-reactive protein
• NCBI Official Symbol: CRP
• NCBI Official Synonym Symbols: PTX1
• NCBI Protein Information: C-reactive protein
• Protein Family: Cryparin

NCBI Description

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]