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Mouse BLOC1S2 Monoclonal Antibody | anti-BLOC1S2 antibody

BLOC1S2 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 2, BLOS2, FLJ30135, MGC10120, RP11-316M21.4) (MaxLight 490)

Gene Names
BLOC1S2; CEAP; BLOS2; CEAP11
Applications
Western Blot
Purity
Purified
Synonyms
BLOC1S2; Monoclonal Antibody; BLOC1S2 (Biogenesis of Lysosomal Organelles Complex-1; Subunit 2; BLOS2; FLJ30135; MGC10120; RP11-316M21.4) (MaxLight 490); Biogenesis of Lysosomal Organelles Complex-1; RP11-316M21.4; anti-BLOC1S2 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
8C10
Specificity
Recognizes BLOC1S2.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-BLOC1S2 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
BLOC1S2 (NP_776170.2, 1aa-142aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Conjugate
MaxLight490
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-BLOC1S2 antibody
BLOC1S2 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]). [supplied by OMIM]
Product Categories/Family for anti-BLOC1S2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18.5 kDa
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 2 isoform 1
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex-1, subunit 2
NCBI Official Symbol
BLOC1S2
NCBI Official Synonym Symbols
CEAP; BLOS2; CEAP11
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 2
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 2
UniProt Gene Name
BLOC1S2
UniProt Synonym Gene Names
BLOS2; CEAP; BLOC-1 subunit 2
UniProt Entry Name
BL1S2_HUMAN

Uniprot Description

BLOC1S2: May play a role in cell proliferation. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Belongs to the BLOC1S2 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10q24.31

Cellular Component: centrosome; recycling endosome; mitochondrion; nucleus; gamma-tubulin complex

Molecular Function: protein C-terminus binding; protein binding; gamma-tubulin binding

Biological Process: induction of apoptosis via death domain receptors; platelet dense granule organization and biogenesis; melanosome organization and biogenesis; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; anterograde synaptic vesicle transport; positive regulation of transcription from RNA polymerase II promoter; microtubule nucleation; anterograde axon cargo transport; neurite development

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Product Notes

The BLOC1S2 bloc1s2 (Catalog #AAA6205325) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BLOC1S2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the BLOC1S2 bloc1s2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLOC1S2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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