Western Blot (WB)
(Western Blot analysis of BLOC1S2 expression in transfected 293T cell line by BLOC1S2 monoclonal antibody (M01), clone 8C10.Lane 1: BLOC1S2 transfected lysate (Predicted MW: 16 KDa).Lane 2: Non-transfected lysate.)
Mouse BLOC1S2 Monoclonal Antibody | anti-BLOC1S2 antibody
BLOC1S2 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 2, BLOS2, FLJ30135, MGC10120, RP11-316M21.4) (PE)
Western Blot (WB)
(Western Blot analysis of BLOC1S2 expression in transfected 293T cell line by BLOC1S2 monoclonal antibody (M01), clone 8C10.Lane 1: BLOC1S2 transfected lysate (Predicted MW: 16 KDa).Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of BLOC1S2 expression in transfected 293T cell line by BLOC1S2 monoclonal antibody (M01), clone 8C10.Lane 1: BLOC1S2 transfected lysate (Predicted MW: 16 KDa).Lane 2: Non-transfected lysate.)
Testing Data
(Detection limit for recombinant GST tagged BLOC1S2 is 0.03 ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged BLOC1S2 is 0.03 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
Uniprot Description
BLOC1S2: May play a role in cell proliferation. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Belongs to the BLOC1S2 family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 10q24.31
Cellular Component: centrosome; recycling endosome; mitochondrion; nucleus; gamma-tubulin complex
Molecular Function: protein C-terminus binding; protein binding; gamma-tubulin binding
Biological Process: induction of apoptosis via death domain receptors; platelet dense granule organization and biogenesis; melanosome organization and biogenesis; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; anterograde synaptic vesicle transport; positive regulation of transcription from RNA polymerase II promoter; microtubule nucleation; anterograde axon cargo transport; neurite development
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Product Notes
The BLOC1S2 bloc1s2 (Catalog #AAA6187451) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BLOC1S2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the BLOC1S2 bloc1s2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLOC1S2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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