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Western Blot (WB) (Western Blot analysis of BCL7B expression in transfected 293T cell line by BCL7B monoclonal antibody (M02), clone 4G1.Lane 1: BCL7B transfected lysate (22.2 KDa).Lane 2: Non-transfected lysate.)

Mouse BCL7B Monoclonal Antibody | anti-BCL7B antibody

BCL7B (B-Cell CLL/Lymphoma 7B) (FITC)

Applications
ELISA, Western Blot
Purity
Purified
Synonyms
BCL7B; Monoclonal Antibody; BCL7B (B-Cell CLL/Lymphoma 7B) (FITC); B-Cell CLL/Lymphoma 7B; anti-BCL7B antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4G1
Specificity
Recognizes BCL7B.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Sequence Length
202
Applicable Applications for anti-BCL7B antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
BCL7B (NP_001698, 124aa-202aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
AHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES
Conjugate
FITC
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.

FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of BCL7B expression in transfected 293T cell line by BCL7B monoclonal antibody (M02), clone 4G1.Lane 1: BCL7B transfected lysate (22.2 KDa).Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of BCL7B expression in transfected 293T cell line by BCL7B monoclonal antibody (M02), clone 4G1.Lane 1: BCL7B transfected lysate (22.2 KDa).Lane 2: Non-transfected lysate.)
Related Product Information for anti-BCL7B antibody
The protein encoded by this gene contains a region that is highly similar to the N-terminal segment of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. The function of this gene has not yet been determined. [provided by RefSeq]
Product Categories/Family for anti-BCL7B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
B-cell CLL/lymphoma 7 protein family member B isoform 1
UniProt Protein Name
B-cell CLL/lymphoma 7 protein family member B
UniProt Gene Name
BCL7B
UniProt Entry Name
BCL7B_HUMAN

Uniprot Description

Function: May play a role in lung tumor development or progression.

Tissue specificity: Ubiquitous. Ref.2 Ref.3

Involvement in disease: BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. Ref.2 Ref.3

Allergenic properties: Causes an allergic reaction in human. Binds to IgE from atopic dermatitis (AD) patients. Identified as an IgE autoantigen in atopic dermatitis (AD) patients with severe skin manifestations. Ref.9

Sequence similarities: Belongs to the BCL7 family.

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Product Notes

The BCL7B bcl7b (Catalog #AAA6178225) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BCL7B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the BCL7B bcl7b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL7B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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