Western Blot (WB)
(Western Blot; Sample: Recombinant ANGPTL8, Human.)
Mouse anti-Human Angiopoietin Like Protein 8 (ANGPTL8) Monoclonal Antibody | anti-ANGPTL8 antibody
Monoclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8)
Gene Names
C19orf80; RIFL; TD26; ANGPTL8; PRO1185; PVPA599
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G Affinity Chromatography
Synonyms
Angiopoietin Like Protein 8 (ANGPTL8); Monoclonal Antibody; Monoclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8); RIFL; TD26; C19orf80; Lipasin; Betatrophin; Hepatocellular Carcinoma-Associated Protein TD26; anti-ANGPTL8 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
C5
Specificity
The antibody is a mouse monoclonal antibody raised against ANGPTL8. It has been selected for its ability to recognize ANGPTL8 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G Affinity Chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence
Met24~Leu196
Applicable Applications for anti-ANGPTL8 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.5-2ug/mL; 1:500-2000
IHC: 5-20ug/mL; 1:50-200
ICC: 5-20ug/mL; 1:50-200
IHC: 5-20ug/mL; 1:50-200
ICC: 5-20ug/mL; 1:50-200
Immunogen Sequence
Met24~Leu196
Cross Reactivity
Human
Conjugation
None
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot; Sample: Recombinant ANGPTL8, Human.)
Western Blot (WB)
(Western Blot; Sample: Recombinant ANGPTL8, Human.)
Western Blot (WB)
(Western Blot; Sample: Lane1: Porcine Liver lysate; Lane2: HepG2 cell lysate; Lane3: A549 cell lysatePrimary Ab: 2?g/ml Mouse Anti-Human ANGPTL8 AntibodySecond Ab: 0.2ug/mL HRP-Linked Rabbit Anti-Mouse IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot; Sample: Lane1: Porcine Liver lysate; Lane2: HepG2 cell lysate; Lane3: A549 cell lysatePrimary Ab: 2?g/ml Mouse Anti-Human ANGPTL8 AntibodySecond Ab: 0.2ug/mL HRP-Linked Rabbit Anti-Mouse IgG Polyclonal Antibody )
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 40ug/ml Mouse Anti-Human ANGPTL8 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 40ug/ml Mouse Anti-Human ANGPTL8 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Product Categories/Family for anti-ANGPTL8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,105 Da
NCBI Official Full Name
angiopoietin-like protein 8
NCBI Official Synonym Full Names
chromosome 19 open reading frame 80
NCBI Official Symbol
C19orf80
NCBI Official Synonym Symbols
RIFL; TD26; ANGPTL8; PRO1185; PVPA599
NCBI Protein Information
angiopoietin-like protein 8; betatrophin variant 1; betatrophin variant 2; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; lipasin; refeeding-induced fat and liver protein
UniProt Protein Name
Angiopoietin-like protein 8
Protein Family
UniProt Gene Name
C19orf80
UniProt Entry Name
BETAT_HUMAN
Uniprot Description
EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: extracellular region
Molecular Function: protein binding; hormone activity
Biological Process: fat cell differentiation; regulation of lipid metabolic process; regulation of lipoprotein metabolic process; cell maturation; cellular lipid metabolic process
Research Articles on ANGPTL8
Similar Products
Product Notes
The ANGPTL8 c19orf80 (Catalog #AAA2111714) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Angiopoietin Like Protein 8 (ANGPTL8) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.5-2ug/mL; 1:500-2000 IHC: 5-20ug/mL; 1:50-200 ICC: 5-20ug/mL; 1:50-200. Researchers should empirically determine the suitability of the ANGPTL8 c19orf80 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Met24~Leu1 96. It is sometimes possible for the material contained within the vial of "Angiopoietin Like Protein 8 (ANGPTL8), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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