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Sequence Information

Angiopoietin Like Protein 8 (ANGPTL8) Recombinant Protein | ANGPTL8 recombinant protein

Recombinant Angiopoietin Like Protein 8 (ANGPTL8)

Gene Names
C19orf80; RIFL; TD26; ANGPTL8; PRO1185; PVPA599
Reactivity
Homo sapiens (Human)
Applications
SDS-Page, Western Blot
Purity
> 90%
Synonyms
Angiopoietin Like Protein 8 (ANGPTL8); Recombinant Angiopoietin Like Protein 8 (ANGPTL8); ANGPTL8 recombinant protein
Ordering
For Research Use Only!
Host
E.coli
Reactivity
Homo sapiens (Human)
Purity/Purification
> 90%
Form/Format
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Concentration
Original Concentration: 200ug/mL (varies by lot)
Applicable Applications for ANGPTL8 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Prokaryotic expression
Residues
Met24~Leu196
Tags
N-terminal His Tag
Subcellular Location
Secreted
Traits
Freeze-dried powder
Predicted isoelectric point
7.3
Usage
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8°C for one month.
Aliquot and store at -80°C for 12 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

Sequence Information

Gene Sequencing (Extract)

Gene Sequencing (Extract)

SDS-PAGE

SDS-PAGE

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 23.4kDa
Accurate Molecular Mass: 25kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
betatrophin
NCBI Official Synonym Full Names
chromosome 19 open reading frame 80
NCBI Official Symbol
C19orf80
NCBI Official Synonym Symbols
RIFL; TD26; ANGPTL8; PRO1185; PVPA599
NCBI Protein Information
betatrophin; lipasin; angiopoietin-like protein 8; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26
UniProt Protein Name
Betatrophin
Protein Family
UniProt Gene Name
C19orf80
UniProt Synonym Gene Names
Angptl8
UniProt Entry Name
BETAT_HUMAN

Uniprot Description

EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: fat cell differentiation; regulation of lipid metabolic process; regulation of lipoprotein metabolic process; cell maturation; cellular lipid metabolic process

Research Articles on ANGPTL8

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Product Notes

The ANGPTL8 c19orf80 (Catalog #AAA2018578) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Angiopoietin Like Protein 8 (ANGPTL8) reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Angiopoietin Like Protein 8 (ANGPTL8) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the ANGPTL8 c19orf80 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angiopoietin Like Protein 8 (ANGPTL8), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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