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2-acylglycerol O-acyltransferase 3 (MOGAT3) Recombinant Protein | MOGAT3 recombinant protein

Recombinant Human 2-acylglycerol O-acyltransferase 3 (MOGAT3)

Gene Names
MOGAT3; DC7; MGAT3; DGAT2L2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
2-acylglycerol O-acyltransferase 3 (MOGAT3); Recombinant Human 2-acylglycerol O-acyltransferase 3 (MOGAT3); MOGAT3 recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
1-341aa; full length protein
Sequence
MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYL VWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMC TGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQ PQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRL KAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQR LHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI
Sequence Length
Full length protein
Application Notes
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Species
Human
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Product Categories/Family for MOGAT3 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,353 Da
NCBI Official Full Name
2-acylglycerol O-acyltransferase 3 isoform b
NCBI Official Synonym Full Names
monoacylglycerol O-acyltransferase 3
NCBI Official Symbol
MOGAT3
NCBI Official Synonym Symbols
DC7; MGAT3; DGAT2L2
NCBI Protein Information
2-acylglycerol O-acyltransferase 3
UniProt Protein Name
2-acylglycerol O-acyltransferase 3
UniProt Gene Name
MOGAT3
UniProt Synonym Gene Names
DC7; DGAT2L7; MGAT3; hDC7
UniProt Entry Name
MOGT3_HUMAN

NCBI Description

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]

Uniprot Description

MOGAT3: Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Belongs to the diacylglycerol acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.3.1.22; EC 2.3.1.20; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: 2-acylglycerol O-acyltransferase activity; diacylglycerol O-acyltransferase activity

Biological Process: glycerol metabolic process; triacylglycerol biosynthetic process

Research Articles on MOGAT3

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Product Notes

The MOGAT3 mogat3 (Catalog #AAA7020622) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-341aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the MOGAT3 mogat3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGVATTLQPP TTSKTLQKQH LEAVGAYQYV LTFLFMGPFF SLLVFVLLFT SLWPFSVFYL VWLYVDWDTP NQGGRRSEWI RNRAIWRQLR DYYPVKLVKT AELPPDRNYV LGAHPHGIMC TGFLCNFSTE SNGFSQLFPG LRPWLAVLAG LFYLPVYRDY IMSFGLCPVS RQSLDFILSQ PQLGQAVVIM VGGAHEALYS VPGEHCLTLQ KRKGFVRLAL RHGASLVPVY SFGENDIFRL KAFATGSWQH WCQLTFKKLM GFSPCIFWGR GLFSATSWGL LPFAVPITTV VGRPIPVPQR LHPTEEEVNH YHALYMTALE QLFEEHKESC GVPASTCLTF I. It is sometimes possible for the material contained within the vial of "2-acylglycerol O-acyltransferase 3 (MOGAT3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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