Ki-67 Protein (Ki67P) Recombinant Protein | Ki67P recombinant protein

Recombinant Ki-67 Protein (Ki67P)

Cat. Num. AAA2097702

• Gene Names: MKI67; KIA; MIB-; MIB-1; PPP1R105
• Reactivity: Human
• Applications: SDS-Page, Western Blot
• Purity: > 95%
• Synonyms: Ki-67 Protein (Ki67P); Recombinant Ki-67 Protein (Ki67P); MKI67; KIA; Ki-67; Antigen Identified By Monoclonal Antibody Ki-67; Ki67P recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: > 95%
• Form/Format: Freeze-dried powder
• Sequence Length: 2896

• Applicable Applications for Ki67P recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Expression System: Prokaryotic expression
• Tag: N-terminal His Tag
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Fragment: Thr2720~Ile3256

Product Categories/Family for Ki67P recombinant protein

Tumor immunity; Reproductive science

NCBI and Uniprot Product Information

• NCBI GI #: 225543215
• NCBI GeneID: 4288
• NCBI Accession #: NP_001139438.1
• NCBI GenBank Nucleotide #: NM_001145966.1
• UniProt Accession #: P46013; Q5VWH2
• Molecular Weight: Predicted Molecular Weight: 64.8kDa
• NCBI Official Full Name: proliferation marker protein Ki-67 isoform 2
• NCBI Official Synonym Full Names: marker of proliferation Ki-67
• NCBI Official Symbol: MKI67
• NCBI Official Synonym Symbols: KIA; MIB-; MIB-1; PPP1R105
• NCBI Protein Information: proliferation marker protein Ki-67; antigen KI-67
• UniProt Protein Name: Proliferation marker protein Ki-67
• UniProt Gene Name: MKI67
• UniProt Synonym Gene Names: Antigen KI-67Curated; Antigen Ki67Curated

NCBI Description

This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]

Uniprot Description

KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers.

Protein type: Cell cycle regulation; Nucleolus

Chromosomal Location of Human Ortholog: 10q26.2

Cellular Component: condensed chromosome; membrane; nuclear body; nucleolus; nucleus

Molecular Function: ATP binding; DNA binding; protein binding; protein C-terminus binding; RNA binding

Biological Process: cell cycle; cell proliferation; regulation of chromatin organization; regulation of chromosome segregation; regulation of mitotic nuclear division