Uniprot Description
Function: Required for accurate chromosome segregation
By similarity.
Subcellular location: Cytoplasm
By similarity. Nucleus
By similarity. Chromosome › centromere › kinetochore
By similarity. Note: Excluded from the nucleus during interphase but migrates into the nuclear zone during prometaphase. At metaphase, found in a filamentous structure that may be specifically associated with kinetochore microtubules. At anaphase, found at or near kinetochores of separating chromosomes. At the beginning of telophase, becomes excluded again from the nucleus and is dispersed in the cytoplasm
By similarity.
Sequence similarities: Belongs to the ZW10 family.
Sequence caution: The sequence EAL32021.1 differs from that shown. Reason: Erroneous gene model prediction.
Product Notes
The Dpsemit(1)15 mit(1)15 (Catalog #
AAA1027311) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-718. The amino acid sequence is listed below: MAARAQIKLL PEMFQSNGCA SLEDTKSTVS KVQTRTERFQ ERVRKHIDEN YSEFMTNHTS PDIFLEESSS LGREINDLLE TVGTEGLAAL NGSSTQLADH SRELRELMLG LQVSEHILKI DELFQCVEEA KGTKDYLVVL DLVGRLRSLI YGEGEAATQD VVRIFQALEC YETIKVKYHV QAHLLQQNMQ ERFDRLVQLN CKSFPNSKCV TLLVSKEEGQ LHDIVIALFQ ERYNPVRLCE FLLENCIEPL ILKPVGVECN ENAEAGTYVQ LSLSYSTKES GTASGTSTQL RPNYKQVLEH FRLLLQTLSG INHSLSSSQH VFSIIGDHVK DRMMHLLVND CLIPAVPETM EEYQASTLCE DVAHFEQYLA DSFLINPEVD RGLSQFIEQY GTYYRNRLCS RVLESTREII QRDLQDMVLV APNNQAMDVT GCDPFLFPRC MVSRSAQDFM KLMERILRQP TEKPGEDEAD PLAGVIGMML QTYIDEVPKV HKKLLESIPQ QSVLFHNNCM YFTHWVAQNA NKGIESFPAL VKTLQATGTM HFRVQVTYQT SILMDIMESF EFESPHTLGT GPLKLVRQCL RQLELLKNVW QNVLPDNVYN STFVELLHAF INELVRHIFT QRDISATMAS DLSDLIDVVL EKAPKLFRDP HEVHQVRSWM KLQQLKTMMN ASLKEITELW CKGAGPLTAN YKADEIRYLI RALFQDTDRR AKAITQIM.
It is sometimes possible for the material contained within the vial of
"Centromere/kinetochore protein zw10 (mit (1)15), Recombinant Protein" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
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aspect of this datasheet at
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