SDS-PAGE
Multiple inositol polyphosphate phosphatase 1 Recombinant Protein | Minpp1 recombinant protein
Recombinant Rat Multiple inositol polyphosphate phosphatase 1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Multiple inositol polyphosphate phosphatase 1; Recombinant Rat Multiple inositol polyphosphate phosphatase 1; 2; 3-bisphosphoglycerate 3-phosphatase (EC:3.1.3.80); 3-BPG phosphataseInositol (1; 3; 4; 5)-tetrakisphosphate 3-phosphatase; Ins(1; 5)P(4) 3-phosphatase; Minpp1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
31-481aa; Full Length
Sequence
SLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLRQLQGLLQTRESVDGGSRVAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLFCRENYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQVAFFTCSFDLAIQGVHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSSVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKVLPLAHSQKTVALYEDLKNHYQDILQSCQTSKECNLPKVNITSDEL
Sequence Length
481
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for Minpp1 recombinant protein
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).
References
Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase.Craxton A., Caffrey J.J., Burkhart W., Safrany S.T., Shears S.B.Biochem. J. 328:75-81(1997)
Hepatic Ins(1,3,4,5)
P4 3-phosphatase is compartmentalized inside endoplasmic reticulum.Ali N., Craxton A., Shears S.B.J. Biol. Chem. 268:6161-6167(1993)
The human and rat forms of multiple inositol polyphosphate phosphatase
functional homology with a histidine acid phosphatase up-regulated during endochondral ossification.Caffrey J.J., Hidaka K., Matsuda M., Hirata M., Shears S.B.FEBS Lett. 442:99-104(1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53.6 kDa
NCBI Official Full Name
multiple inositol polyphosphate phosphatase 1
NCBI Official Synonym Full Names
multiple inositol-polyphosphate phosphatase 1
NCBI Official Symbol
Minpp1
NCBI Protein Information
multiple inositol polyphosphate phosphatase 1
UniProt Protein Name
Multiple inositol polyphosphate phosphatase 1
Protein Family
UniProt Gene Name
Minpp1
UniProt Synonym Gene Names
Mipp1; 2,3-BPG phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase
UniProt Entry Name
MINP1_RAT
NCBI Description
catalyzes the hydrolysis of Ins(1,3,4,5,6)P5, first to Ins(1,4,5,6)P4 and then to Ins(1,4,5)P3, by consecutive 3- and 6-phosphatase activities [RGD, Feb 2006]
Uniprot Description
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy ().
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Product Notes
The Minpp1 minpp1 (Catalog #AAA1037664) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 31-481aa; Full Length. The amino acid sequence is listed below: SLPGRGDPVA SVLSPYFGTK TRYEDVNPWL LGDPVAPRRD PELLAGTCTP VQLVALIRHG TRYPTTKQIR KLRQLQGLLQ TRESVDGGSR VAAALDQWPL WYDDWMDGQL VEKGRQDMRQ LALRLAALFP DLFCRENYGR LRLITSSKHR CVDSSAAFLQ GLWQHYHPGL PPPDVSDMEC DPPRVNDKLM RFFDHCEKFL TEVERNATAL YHVEAFKTGP EMQTVLKKVA ATLQVPVNNL NADLIQVAFF TCSFDLAIQG VHSPWCDVFD VDDAKVLEYL NDLKQYWKRS YGYAINSRSS CNLFQDIFLH LDKAVEQKQR SQPVSSSVIL QFGHAETLLP LLSLMGYFKD KEPLTAYNFE EQVHREFRSG HIVPYASNLI FVLYHCEDAQ TPQEKFQIQM LLNEKVLPLA HSQKTVALYE DLKNHYQDIL QSCQTSKECN LPKVNITSDE L. It is sometimes possible for the material contained within the vial of "Multiple inositol polyphosphate phosphatase 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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