Methylated-DNA--protein-cysteine methyltransferase (MGMT) Recombinant Protein | MGMT recombinant protein
Recombinant Dog Methylated-DNA--protein-cysteine methyltransferase (MGMT)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Methylated-DNA--protein-cysteine methyltransferase (MGMT); Recombinant Dog Methylated-DNA--protein-cysteine methyltransferase (MGMT); MGMT recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-216, Full length protein
Sequence
MDKACKMRYKTMDSPLGKIEISGCAQGLHEIRLHDRKTPDPGPAEAPAPPELLGCPEEMTEPLVQCVAWLDAYFREPSVLPGLPLPAIHHPIFQRGSFTARVLRKLLELVKFGDTVSYQQLAALAGNPKAARAVGGAMRSNPVPILIPCHRVVCSSGAMGNYTGGLATKEWLLAHEGRLAGKPTYPGGSYLAGTRRGALGGTPSPHPAGRDGCVRE
Sequence Length
216
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,052 Da
NCBI Official Full Name
methylated-DNA--protein-cysteine methyltransferase
NCBI Official Synonym Full Names
O-6-methylguanine-DNA methyltransferase
NCBI Official Symbol
MGMT
NCBI Protein Information
methylated-DNA--protein-cysteine methyltransferase
UniProt Protein Name
Methylated-DNA--protein-cysteine methyltransferase
Protein Family
UniProt Gene Name
MGMT
UniProt Synonym Gene Names
MGMT
Uniprot Description
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Research Articles on MGMT
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Product Notes
The MGMT mgmt (Catalog #AAA1302271) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-216, Full length protein. The amino acid sequence is listed below: MDKACKMRYK TMDSPLGKIE ISGCAQGLHE IRLHDRKTPD PGPAEAPAPP ELLGCPEEMT EPLVQCVAWL DAYFREPSVL PGLPLPAIHH PIFQRGSFTA RVLRKLLELV KFGDTVSYQQ LAALAGNPKA ARAVGGAMRS NPVPILIPCH RVVCSSGAMG NYTGGLATKE WLLAHEGRLA GKPTYPGGSY LAGTRRGALG GTPSPHPAGR DGCVRE. It is sometimes possible for the material contained within the vial of "Methylated-DNA--protein-cysteine methyltransferase (MGMT), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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