SDS-Page
MFAP2 recombinant protein
MFAP2, 18-183aa, Human, His tag, E Coli (Denatured)
Gene Names
MFAP2; MAGP; MAGP1; MAGP-1
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
MFAP2; 18-183aa; Human; His tag; E Coli (Denatured); Microfibrillar-associated protein 2; MAGP; MAGP-1; MAGP1; MFAP2 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1M urea, 20% glycerol
Concentration
0.5 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMQGQYDL DPLPPFPDHV QYTHYSDQID NPDYYDYQEV TPRPSEEQFQ FQSQQQVQQE VIPAPTPEPG NAELEPTEPG PLDCREEQYP CTRLYSIHRP CKQCLNEVCF YSLRRVYVIN KEICVRTVCA HEELLRADLC RDKFSKCGVM ASSGLCQSVA ASCARSCGSC
Sequence Length
183
Applicable Applications for MFAP2 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for MFAP2 recombinant protein
Microfibrillar-associated protein 2, also known as MFAP2, is an O-glycosylated protein secreted to the extracellular space and the extracellular matrix. MFAP2 associates with biglycan and elastin in a ternary complex. It is shown to play a significant role in the support and distensibility of the juxtacanalicular region of these collector channels. It is also reported to inhibit LTB-1 binding to fibrillin-1, stimulate the phosphorylation of Smad2, and thereby mediate the subsequent extracellular deposition of latent TGFbeta. Recombinant human MFAP2, fused to His-tag at N-terminus, was expressed in E Coli.
Product Categories/Family for MFAP2 recombinant protein
References
Segade F., et al. (2002) J Biol Chem. 277:11050-11057.; Penner A S., et al. (2002) J Biol Chem. 277:35044-35049.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21.5 kDa (190aa)
NCBI Official Full Name
microfibrillar-associated protein 2 isoform a
NCBI Official Synonym Full Names
microfibril associated protein 2
NCBI Official Symbol
MFAP2
NCBI Official Synonym Symbols
MAGP; MAGP1; MAGP-1
NCBI Protein Information
microfibrillar-associated protein 2
UniProt Protein Name
Microfibrillar-associated protein 2
Protein Family
UniProt Gene Name
MFAP2
UniProt Synonym Gene Names
MAGP1; MFAP-2; MAGP; MAGP-1
NCBI Description
Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Uniprot Description
Component of the elastin-associated microfibrils.
Research Articles on MFAP2
Similar Products
Product Notes
The MFAP2 mfap2 (Catalog #AAA204910) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's MFAP2 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the MFAP2 mfap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSMQGQYDL DPLPPFPDHV QYTHYSDQID NPDYYDYQEV TPRPSEEQFQ FQSQQQVQQE VIPAPTPEPG NAELEPTEPG PLDCREEQYP CTRLYSIHRP CKQCLNEVCF YSLRRVYVIN KEICVRTVCA HEELLRADLC RDKFSKCGVM ASSGLCQSVA ASCARSCGSC. It is sometimes possible for the material contained within the vial of "MFAP2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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