SDS-Page
(Recombinant METTL21D (VCPKMT) protein gel 10% SDS-PAGE gel withCoomassie blue staining MW: 27 kDa Purity: >90%)
METTL21D recombinant protein
Recombinant METTL21D (VCPKMT) protein
Synonyms
METTL21D; Recombinant METTL21D (VCPKMT) protein; METTL21D recombinant protein
Host
Baculovirus
Form/Format
Recombinant METTL21D (VCPKMT) protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP.
Protein Species
Human
Tag
DYKDDDDK-Tag
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data this product is shown.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant METTL21D (VCPKMT) protein gel 10% SDS-PAGE gel withCoomassie blue staining MW: 27 kDa Purity: >90%)
SDS-Page
(Recombinant METTL21D (VCPKMT) protein gel 10% SDS-PAGE gel withCoomassie blue staining MW: 27 kDa Purity: >90%)
Related Product Information for METTL21D recombinant protein
Short Description: Recombinant METTL21D (VCPKMT) protein was expressed in a baculovirus expression system as the full-length human protein (accession number NP_078834.2) with an N-terminal DYKDDDDK-Tag. The molecular weight of the protein is 27 kDa.
Background: METTL21D (Methyltransferase-Like Protein 21D), also known as VCPKMT (Valosin Containing Protein Lysine Methyltransferase), is a member of the Family 16 group of methyltransferases. It is responsible for the trimethylation of VCP (also called p97) on Lys 315. VCP is a highly conserved member of the AAA+-ATPases (ATPases associated with various activities) family, involved in several cellular pathways including protein degradation, endoplasmic reticulum-associated degradation, cell cycle regulation, membrane fusion and DNA damage response. Recently, it has been shown that VCPKMT is involved in cancer metastasis formation, but the physiological role of K315me3 in VCP has not been established and also the effect of K315me3 on the ATPase activity of VCP is not yet clear.
Background: METTL21D (Methyltransferase-Like Protein 21D), also known as VCPKMT (Valosin Containing Protein Lysine Methyltransferase), is a member of the Family 16 group of methyltransferases. It is responsible for the trimethylation of VCP (also called p97) on Lys 315. VCP is a highly conserved member of the AAA+-ATPases (ATPases associated with various activities) family, involved in several cellular pathways including protein degradation, endoplasmic reticulum-associated degradation, cell cycle regulation, membrane fusion and DNA damage response. Recently, it has been shown that VCPKMT is involved in cancer metastasis formation, but the physiological role of K315me3 in VCP has not been established and also the effect of K315me3 on the ATPase activity of VCP is not yet clear.
Product Categories/Family for METTL21D recombinant protein
NCBI and Uniprot Product Information
Molecular Weight
Molecular weight of the protein is 27kDa
Similar Products
Product Notes
The METTL21D (Catalog #AAA389259) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "METTL21D, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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