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Methionine aminopeptidase 1D, mitochondrial (METAP1D) Recombinant Protein | METAP1D recombinant protein

Recombinant Human Methionine aminopeptidase 1D, mitochondrial (METAP1D)

Gene Names
METAP1D; MAP1D; MAP 1D; Metap1l; MetAP 1D
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Methionine aminopeptidase 1D; mitochondrial (METAP1D); Recombinant Human Methionine aminopeptidase 1D; METAP1D recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
20-335, Full length protein
Sequence
SSPLNHIYLHKQSSSQQRRNFFFRRQRDISHSIVLPAAVSSAHPVPKHIKKPDYVTTGIVPDWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMTTEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITSRGAQILTKLPHEA
Sequence Length
316
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,088 Da
NCBI Official Full Name
methionine aminopeptidase 1D, mitochondrial isoform 2
NCBI Official Synonym Full Names
methionyl aminopeptidase type 1D, mitochondrial
NCBI Official Symbol
METAP1D
NCBI Official Synonym Symbols
MAP1D; MAP 1D; Metap1l; MetAP 1D
NCBI Protein Information
methionine aminopeptidase 1D, mitochondrial
UniProt Protein Name
Methionine aminopeptidase 1D, mitochondrial
UniProt Gene Name
METAP1D
UniProt Synonym Gene Names
MAP1D; MAP 1D; MetAP 1D

NCBI Description

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008]

Uniprot Description

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (). May play a role in colon tumorigenesis.

Research Articles on METAP1D

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Product Notes

The METAP1D metap1d (Catalog #AAA1418537) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 20-335, Full length protein. The amino acid sequence is listed below: SSPLNHIYLH KQSSSQQRRN FFFRRQRDIS HSIVLPAAVS SAHPVPKHIK KPDYVTTGIV PDWGDSIEVK NEDQIQGLHQ ACQLARHVLL LAGKSLKVDM TTEEIDALVH REIISHNAYP SPLGYGGFPK SVCTSVNNVL CHGIPDSRPL QDGDIINIDV TVYYNGYHGD TSETFLVGNV DECGKKLVEV ARRCRDEAIA ACRAGAPFSV IGNTISHITH QNGFQVCPHF VGHGIGSYFH GHPEIWHHAN DSDLPMEEGM AFTIEPIITE GSPEFKVLED AWTVVSLDNQ RSAQFEHTVL ITSRGAQILT KLPHEA. It is sometimes possible for the material contained within the vial of "Methionine aminopeptidase 1D, mitochondrial (METAP1D), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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