Mouse Meis homeobox 1 ELISA Kit | MEIS1 elisa kit
Mouse Homeobox protein Meis1, MEIS1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MEIS1: Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. Defects in MEIS1 could be a cause of susceptibility to restless legs syndrome type 7 (RLS7). Restless legs syndrome (RLS) is a neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, usually at night, inducing an irresistible desire to move the legs. The disorder results in nocturnal insomnia and chronic sleep deprivation. Belongs to the TALE/MEIS homeobox family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Cellular Component: transcription factor complex; nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; chromatin binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; negative regulation of neuron differentiation; negative regulation of myeloid cell differentiation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; blood vessel morphogenesis; positive regulation of transcription from RNA polymerase II promoter; hemopoiesis; lens morphogenesis in camera-type eye; locomotory behavior; angiogenesis
Research Articles on MEIS1
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Product Notes
The Mouse MEIS1 meis1 (Catalog #AAA9339490) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339490 ELISA Kit recognizes Mouse MEIS1. It is sometimes possible for the material contained within the vial of "Meis homeobox 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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