Western Blot (WB)
((2ug/ml) staining of Human Colorectal Cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat THNSL2 Polyclonal Antibody | anti-THNSL2 antibody
Goat anti-THNSL2 (aa192-204) Antibody
Western Blot: Approx 40kDa band observed in Human Colorectal cancer lysates (calculated MW of 45. 0kDa according to NP_001231605.1). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((2ug/ml) staining of Human Colorectal Cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((2ug/ml) staining of Human Colorectal Cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Uniprot Description
THNSL2: Isoform 1: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho- threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate. Belongs to the threonine synthase family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 4.2.3.-; Lyase
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: cytoplasm; extracellular space
Molecular Function: cytokine activity; pyridoxal phosphate binding; threonine synthase activity
Biological Process: 2-oxobutyrate biosynthetic process; dephosphorylation; serine family amino acid catabolic process; threonine biosynthetic process
Research Articles on THNSL2
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Product Notes
The THNSL2 thnsl2 (Catalog #AAA423023) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-THNSL2 (aa192-204) Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's THNSL2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 40kDa band observed in Human Colorectal cancer lysates (calculated MW of 45. 0kDa according to NP_001231605.1). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the THNSL2 thnsl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EGNSDELDEP IKT. It is sometimes possible for the material contained within the vial of "THNSL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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