Putative ATP:guanido phosphotransferase yacI (yacI) Recombinant Protein | yacI recombinant protein
Recombinant Bacillus subtilis Putative ATP:guanido phosphotransferase yacI (yacI)
NCBI and Uniprot Product Information
Uniprot Description
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system, where it is involved in regulating the global heat shock repressor CtsR; phosphorylates arginine residues in the winged helix-turn-helix domain of CtsR, thereby preventing its binding to DNA and consequently inducing the expression of repressed genes. The transcriptional repressor HrcA, the chaperone GroEL, the unfoldase ClpC, together with several ribosomal subunits, represent other physiological targets of McsB under stress conditions. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. Functions as an adapter whose kinase activity is required for ClpCP-mediated degradation of CtsR during heat stress. Is required for the delocalization of competence proteins from the cell poles, probably via a role in the degradation of anchor proteins.
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Product Notes
The yacI mcsb (Catalog #AAA1042379) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-363, Full length protein. The amino acid sequence is listed below: MSLKHFIQDA LSSWMKQKGP ESDIVLSSRI RLARNFEHIR FPTRYSNEEA SSIIQQFEDQ FSEQEIPGIG KFVLIRMNDA QPLEKRVLVE KHLISPNLTE SPFGGCLLSE NEEVSVMLNE EDHIRIQCLF PGFQLLEAMK AANQVDDWIE EKVDYAFNEQ RGYLTSCPTN VGTGLRASVM MHLPALVLTR QINRIIPAIN QLGLVVRGIY GEGSEAVGNI FQISNQITLG KSEQDIVEDL NSVAAQLIEQ ERSAREAIYQ TSKIELEDRV YRSYGVLSNC RMIESKETAK CLSDVRLGID LGIIKGLSSN ILNELMILTQ PGFLQQYSGG ALRPNERDIR RAALIRERLH LEMNGKRQED ESI. It is sometimes possible for the material contained within the vial of "Putative ATP:guanido phosphotransferase yacI (yacI), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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