Mitochondrial antiviral-signaling protein (Mavs) Recombinant Protein | Mavs recombinant protein
Recombinant Rat Mitochondrial antiviral-signaling protein (Mavs), partial
Gene Names
Mavs; Visa
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Mitochondrial antiviral-signaling protein (Mavs); Recombinant Rat Mitochondrial antiviral-signaling protein (Mavs); partial; Mavs recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-482
Sequence
MTFAEEKTYK YIRYNHSKFC CVDVLEILPY LSCLTTSDQD RLRASYKQLG NQGTLWELFN TLQRRPGWVE VFIRALRICE LPGLAEQVTR VYQSYLPPGA SLHSLDPLQS PRIPTTVSEP SAFAAGHTIP DSGFQDKPGY PKPVQDTQPP KSPVENSEEP PQANFGAIPR MSGDSLISSP NPPALSPQPS REHPEQEPEL GGPSTANVDS VPIATYGPVS PTVSFQPLPR IAPRTNLSPG VTVSALSAKT TLSSSSTGSA FAKGAGDQAK AATCVSTKEG VPTNSVTTSS VPSIKPVPVN TMSSKLPIST KSTAATPSTV PTNIAPSKLP INSVYTGIVP SKVTASVAKA SASTMPPERN NKQAKETLEA PATVVTTGSS LTRPDISSRS LHSGPELSKP GVLVSQVDNE PFSACSMDLA ISPSTSLGSE PNHGPEENEY SSFRIQVDKS PSVDLLGSPE PLATQQSPEE EEPCASSVSW AK
Sequence Length
482
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,805 Da
NCBI Official Full Name
mitochondrial antiviral-signaling protein
NCBI Official Synonym Full Names
mitochondrial antiviral signaling protein
NCBI Official Symbol
Mavs
NCBI Official Synonym Symbols
Visa
NCBI Protein Information
mitochondrial antiviral-signaling protein
UniProt Protein Name
Mitochondrial antiviral-signaling protein
Protein Family
UniProt Gene Name
Mavs
UniProt Synonym Gene Names
Ips1; Visa; MAVS; IPS-1; VISA
Uniprot Description
Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.
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Product Notes
The Mavs mavs (Catalog #AAA1391494) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-482. The amino acid sequence is listed below: MTFAEEKTYK YIRYNHSKFC CVDVLEILPY LSCLTTSDQD RLRASYKQLG NQGTLWELFN TLQRRPGWVE VFIRALRICE LPGLAEQVTR VYQSYLPPGA SLHSLDPLQS PRIPTTVSEP SAFAAGHTIP DSGFQDKPGY PKPVQDTQPP KSPVENSEEP PQANFGAIPR MSGDSLISSP NPPALSPQPS REHPEQEPEL GGPSTANVDS VPIATYGPVS PTVSFQPLPR IAPRTNLSPG VTVSALSAKT TLSSSSTGSA FAKGAGDQAK AATCVSTKEG VPTNSVTTSS VPSIKPVPVN TMSSKLPIST KSTAATPSTV PTNIAPSKLP INSVYTGIVP SKVTASVAKA SASTMPPERN NKQAKETLEA PATVVTTGSS LTRPDISSRS LHSGPELSKP GVLVSQVDNE PFSACSMDLA ISPSTSLGSE PNHGPEENEY SSFRIQVDKS PSVDLLGSPE PLATQQSPEE EEPCASSVSW AK. It is sometimes possible for the material contained within the vial of "Mitochondrial antiviral-signaling protein (Mavs), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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