Western Blot (WB)
(Western Blot (WB) analysis of MAVS polyclonal antibody)
Rabbit MAVS Polyclonal Antibody | anti-MAVS antibody
MAVS Polyclonal Antibody
Gene Names
MAVS; IPS1; VISA; IPS-1; CARDIF
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
MAVS; Polyclonal Antibody; MAVS Polyclonal Antibody; CARD adapter inducing interferon beta; Cardif; DKFZp666M015; FLJ27482; FLJ41962; Interferon beta promoter stimulator protein 1; Interferon-beta promoter stimulator protein 1; Ips 1; IPS-1; Ips1; KIAA1271; MAVS_HUMAN; Mitochondrial anti viral signaling protein; Mitochondrial Antiviral Signaling; Mitochondrial antiviral signaling protein; Mitochondrial antiviral-signaling protein; Putative NF kappa B activating protein 031N; Putative NF-kappa-B-activating protein 031N; Virus induced signaling adapter; Virus-induced-signaling adapter; VISA; anti-MAVS antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MAVS polyclonal antibody detects endogenous levels of MAVS protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
399
Applicable Applications for anti-MAVS antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant full length Human MAVS.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of MAVS polyclonal antibody)
Western Blot (WB)
(Western Blot (WB) analysis of MAVS polyclonal antibody)
Related Product Information for anti-MAVS antibody
MAVS (mitochondrial antiviral-signaling protein), also known as IPS1, KIAA1271, VISA or CARDIF, is a 540 amino acid protein that contains one CARD domain and several transmembrane domains, and localizes to the outer mitochondrial membrane. Expressed throughout the body with highest ex-pression in liver, heart, placenta, skeletal muscle and peripheral blood leuk-ocytes, MAVS functions downstream of proteins, such as RIG-I, that detect double-stranded (ds) viral replication and is required for proper immune re-sponse against ds viral infection. MAVS is thought to activate pathways that lead to the induction of antiviral cytokines and may protect the cells from viral-induced apoptosis. MAVS function can be inactivated via cleavage by a protease complex that degrades the CARD and transmembrane domains, thereby preventing MAVS from interacting with other proteins. Three isoforms of MAVS are expressed due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 70kDa
NCBI Official Full Name
mitochondrial antiviral-signaling protein isoform 2
NCBI Official Synonym Full Names
mitochondrial antiviral signaling protein
NCBI Official Symbol
MAVS
NCBI Official Synonym Symbols
IPS1; VISA; IPS-1; CARDIF
NCBI Protein Information
mitochondrial antiviral-signaling protein
UniProt Protein Name
Mitochondrial antiviral-signaling protein
Protein Family
UniProt Gene Name
MAVS
UniProt Synonym Gene Names
IPS1; KIAA1271; VISA; MAVS; Cardif; IPS-1; VISA
UniProt Entry Name
MAVS_HUMAN
NCBI Description
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Research Articles on MAVS
Similar Products
Product Notes
The MAVS mavs (Catalog #AAA3011329) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAVS Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAVS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:200. Researchers should empirically determine the suitability of the MAVS mavs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAVS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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