SDS-PAGE
Mannan-binding lectin serine protease 2 (Masp2) Recombinant Protein | Masp2 recombinant protein
Recombinant Mouse Mannan-binding lectin serine protease 2 (Masp2)
Gene Names
Masp2; MAp19; MASP-2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Mannan-binding lectin serine protease 2 (Masp2); Recombinant Mouse Mannan-binding lectin serine protease 2 (Masp2); Mannan-binding lectin serine protease 2; EC=3.4.21.104; MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2; MASP-2Cleaved into the following 2 chains:; 1. Mannan-binding lectin serine protease 2 A chain; 2. Mannan-bindi; Masp2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
20-685aa; Full Length
Sequence
SKWPEPVFGRLVSPGFPEKYADHQDRSWTLTAPPGYRLRLYFTHFDLELSYRCEYDFVKLSSGTKVLATLCGQESTDTEQAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRVSLGDSVPCDHYCHNYLGGYYCSCRAGYVLHQNKHTCSALCSGQVFTGRSGYLSSPEYPQPYPKLSSCTYSIRLEDGFSVILDFVESFDVETHPEAQCPYDSLKIQTDKGEHGPFCGKTLPPRIETDSHKVTITFATDESGNHTGWKIHYTSTARPCPDPTAPPNGSISPVQAIYVLKDRFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPMPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKLPPVCEPVCGLSTHTIGGRIVGGQPAKPGDFPWQVLLLGQTTAAAGALIHDNWVLTAAHAVYEKRMAASSLNIRMGILKRLSPHYTQAWPEEIFIHEGYTHGAGFDNDIALIKLKNKVTINGSIMPVCLPRKEAASLMRTDFTGTVAGWGLTQKGLLARNLMFVDIPIADHQKCTAVYEKLYPGVRVSANMLCAGLETGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGAADQYGVYTKVINYIPWIENIISNF
Sequence Length
666
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
SDS-PAGE
SDS-PAGE
Related Product Information for Masp2 recombinant protein
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase
Product Categories/Family for Masp2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75.4 kDa
NCBI Official Full Name
mannan-binding lectin serine protease 2 isoform 1
NCBI Official Synonym Full Names
mannan-binding lectin serine peptidase 2
NCBI Official Symbol
Masp2
NCBI Official Synonym Symbols
MAp19; MASP-2
NCBI Protein Information
mannan-binding lectin serine protease 2; MBL-associated serine protease 2; mannose-binding protein-associated serine protease 2
UniProt Protein Name
Mannan-binding lectin serine protease 2
Protein Family
UniProt Gene Name
Masp2
UniProt Synonym Gene Names
MASP-2
UniProt Entry Name
MASP2_MOUSE
Uniprot Description
MASP2: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. Defects in MASP2 are the cause of MASP2 deficiency (MASPD). MASPD is a disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.104; Secreted; Secreted, signal peptide; Protease
Cellular Component: extracellular region
Molecular Function: peptidase activity; protein binding; hydrolase activity; serine-type peptidase activity; metal ion binding; serine-type endopeptidase activity; complement component C4b binding; calcium ion binding; calcium-dependent protein binding; catalytic activity
Biological Process: immune system process; innate immune response; proteolysis; complement activation, lectin pathway; complement activation, classical pathway; complement activation
Research Articles on Masp2
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Product Notes
The Masp2 masp2 (Catalog #AAA1375096) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 20-685aa; Full Length. The amino acid sequence is listed below: SKWPEPVFGR LVSPGFPEKY ADHQDRSWTL TAPPGYRLRL YFTHFDLELS YRCEYDFVKL SSGTKVLATL CGQESTDTEQ APGNDTFYSL GPSLKVTFHS DYSNEKPFTG FEAFYAAEDV DECRVSLGDS VPCDHYCHNY LGGYYCSCRA GYVLHQNKHT CSALCSGQVF TGRSGYLSSP EYPQPYPKLS SCTYSIRLED GFSVILDFVE SFDVETHPEA QCPYDSLKIQ TDKGEHGPFC GKTLPPRIET DSHKVTITFA TDESGNHTGW KIHYTSTARP CPDPTAPPNG SISPVQAIYV LKDRFSVFCK TGFELLQGSV PLKSFTAVCQ KDGSWDRPMP ECSIIDCGPP DDLPNGHVDY ITGPEVTTYK AVIQYSCEET FYTMSSNGKY VCEADGFWTS SKGEKLPPVC EPVCGLSTHT IGGRIVGGQP AKPGDFPWQV LLLGQTTAAA GALIHDNWVL TAAHAVYEKR MAASSLNIRM GILKRLSPHY TQAWPEEIFI HEGYTHGAGF DNDIALIKLK NKVTINGSIM PVCLPRKEAA SLMRTDFTGT VAGWGLTQKG LLARNLMFVD IPIADHQKCT AVYEKLYPGV RVSANMLCAG LETGGKDSCR GDSGGALVFL DNETQRWFVG GIVSWGSINC GAADQYGVYT KVINYIPWIE NIISNF. It is sometimes possible for the material contained within the vial of "Mannan-binding lectin serine protease 2 (Masp2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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