Mouse mitogen-activated protein kinase kinase 4 ELISA Kit | MAP2K4 elisa kit
Mouse Dual specificity mitogen-activated protein kinase kinase 4, MAP2K4 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MKK4: dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38 but not ERK1 or -2. Mediates cellular responses to various cellular stresses and inflammatory cytokines. Phosphorylation by Akt inhibits MKK4 and suppresses stress-activated signal transduction.
Protein type: Kinase, protein; Protein kinase, dual-specificity (non-receptor); Protein kinase, STE; EC 2.7.12.2; STE group; STE7 family
Cellular Component: dendrite cytoplasm; axon; cytoplasm; perikaryon; intracellular; cytosol; nucleus
Molecular Function: MAP kinase kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; mitogen-activated protein kinase kinase kinase binding; JUN kinase kinase activity; ATP binding; protein kinase activity
Biological Process: apoptosis; positive regulation of apoptosis; positive regulation of neuron apoptosis; MAPKKK cascade; JNK cascade; positive regulation of protein amino acid phosphorylation; phosphorylation; protein amino acid phosphorylation; positive regulation of DNA replication; activation of JNK activity; positive regulation of nitric-oxide synthase biosynthetic process
Research Articles on MAP2K4
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Product Notes
The Mouse MAP2K4 map2k4 (Catalog #AAA9328826) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328826 ELISA Kit recognizes Mouse MAP2K4. It is sometimes possible for the material contained within the vial of "mitogen-activated protein kinase kinase 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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