Microtubule-associated protein 1B (MAP1B) Recombinant Protein | MAP1B\r recombinant protein

Recombinant Human Microtubule-associated protein 1B (MAP1B) , partial

• Gene Names: MAP1B; MAP5; FUTSCH; PPP1R102
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Microtubule-associated protein 1B (MAP1B); Recombinant Human Microtubule-associated protein 1B (MAP1B); partial; MAP1B\r recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 2,468

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for MAP1B\r recombinant protein

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system.

NCBI and Uniprot Product Information

• NCBI GI #: 153945728
• NCBI GeneID: 4131
• NCBI Accession #: NP_005900.2
• NCBI GenBank Nucleotide #: NM_005909.4
• UniProt Accession #: P46821; A2BDK5
• Molecular Weight: 270,634 Da
• NCBI Official Full Name: microtubule-associated protein 1B isoform 1
• NCBI Official Synonym Full Names: microtubule associated protein 1B
• NCBI Official Symbol: MAP1B
• NCBI Official Synonym Symbols: MAP5; FUTSCH; PPP1R102
• NCBI Protein Information: microtubule-associated protein 1B
• UniProt Protein Name: Microtubule-associated protein 1B
• UniProt Gene Name: MAP1B
• UniProt Synonym Gene Names: MAP-1B

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

Facilitates tyrosination of alpha-tubulin in neuronal microtubules (). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.