Goat Monoamine oxidase A ELISA Kit | MAOA elisa kit

Goat Monoamine oxidase A ELISA Kit

Cat. Num. AAA749594

• Gene Names: MAOA; MAO-A
• Reactivity: Goat
• Synonyms: Monoamine oxidase A; Goat Monoamine oxidase A ELISA Kit; MAOA elisa kit

• Reactivity: Goat

• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Product Categories/Family for MAOA elisa kit

Neurobiology

NCBI and Uniprot Product Information

• NCBI GI #: 4262061
• NCBI GeneID: 4128
• UniProt Accession #: P21397; Q16426; B4DF46
• Molecular Weight: 59,682 Da
• NCBI Official Full Name: monoamine oxidase A, partial
• NCBI Official Synonym Full Names: monoamine oxidase A
• NCBI Official Symbol: MAOA
• NCBI Official Synonym Symbols: MAO-A
• NCBI Protein Information: amine oxidase [flavin-containing] A; amine oxidase [flavin-containing] A; monoamine oxidase type A
• UniProt Protein Name: Amine oxidase [flavin-containing] A
• Protein Family: Amine oxidase
• UniProt Gene Name: MAOA
• UniProt Synonym Gene Names: MAO-A
• UniProt Entry Name: AOFA_HUMAN

NCBI Description

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Uniprot Description

MAOA: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Defects in MAOA are the cause of Brunner syndrome (BRUNS). Brunner syndrome is a form of X-linked non- dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Belongs to the flavin monoamine oxidase family.

Protein type: Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline; Membrane protein, integral; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - phenylalanine; EC 1.4.3.4; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - tyrosine

Chromosomal Location of Human Ortholog: Xp11.3

Cellular Component: mitochondrial outer membrane; mitochondrion; integral to membrane

Molecular Function: amine oxidase activity

Biological Process: synaptic transmission; biogenic amine metabolic process; neurotransmitter catabolic process; dopamine catabolic process; neurotransmitter secretion; xenobiotic metabolic process; neurotransmitter biosynthetic process

Disease: Brunner Syndrome