Repressor of RNA polymerase III transcription MAF1 homolog Recombinant Protein | MAF1 recombinant protein

Recombinant Human Repressor of RNA polymerase III transcription MAF1 homolog

Cat. Num. AAA1391495

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Repressor of RNA polymerase III transcription MAF1 homolog; Recombinant Human Repressor of RNA polymerase III transcription MAF1 homolog; MAF1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-256aa; Full Length
• Sequence: MKLLENSSFEAINSQLTVETGDAHIIGRIESYSCKMAGDDKHMFKQFCQEGQPHVLEALSPPQTSGLSPSRLSKSQGGEEEGPLSDKCSRKTLFYLIATLNESFRPDYDFSTARSHEFSREPSLSWVVNAVNCSLFSAVREDFKDLKPQLWNAVDEEICLAECDIYSYNPDLDSDPFGEDGSLWSFNYFFYNKRLKRIVFFSCRSISGSTYTPSEAGNELDMELGEEEVEEESRSGGSGAEETSTMEEDRVPVICI
• Sequence Length: 256

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for MAF1 recombinant protein

element of the mTORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.

Product Categories/Family for MAF1 recombinant protein

Transcription

References

Towards a catalog of human genes and proteins sequencing and analysis of 500 novel complete protein coding human cDNAs.Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B., Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A.Genome Res. 11:422-435(2001)

NCBI and Uniprot Product Information

• NCBI GI #: 110349740
• NCBI GeneID: 84232
• NCBI Accession #: NP_115648.2
• NCBI GenBank Nucleotide #: NM_032272.4
• UniProt Accession #: Q9H063; D3DWL4
• Molecular Weight: 44.8 kDa
• NCBI Official Full Name: repressor of RNA polymerase III transcription MAF1 homolog
• NCBI Official Synonym Full Names: MAF1 homolog, negative regulator of RNA polymerase III
• NCBI Official Symbol: MAF1
• NCBI Protein Information: repressor of RNA polymerase III transcription MAF1 homolog
• UniProt Protein Name: Repressor of RNA polymerase III transcription MAF1 homolog
• Protein Family: Repressor of RNA polymerase III transcription
• UniProt Gene Name: MAF1
• UniProt Entry Name: MAF1_HUMAN

NCBI Description

This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008]

Uniprot Description

MAF1: Element of the mTORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: axon; centrosome; cytoplasm; cytosol; dendrite; intracellular; intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane

Molecular Function: GABA receptor binding

Biological Process: negative regulation of transcription from RNA polymerase III promoter; transcription, DNA-dependent